Passing this on…I have never heard of this before

 

From: Fully Vetted [mailto:[email protected]] 
Sent: Thursday, March 01, 2012 6:21 AM
To: [email protected]
Subject: Geography Matters with Blastomycosis

 


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 Geography Matters with Blastomycosis 
March 01, 2012

When most pet owners think "infection," bacteria and viruses come to mind. But 
fungi are also sometimes to blame. I’m not talking mushrooms here, but 
microscopic fungal organisms that can invade the body and cause disease.

 

Some fungal infections (e.g., ringworm or yeast infections of the skin and 
ears) are common, and while they can certainly be detrimental to an 
individual’s quality of life and expensive to treat, they are not generally 
life threatening. Other fungal diseases are much more serious. One of these is  
<http://www.petmd.com/dog/conditions/respiratory/c_multi_blastomycosis?utm_source=Newsletter&utm_medium=Email&utm_content=20120301&utm_campaign=FullyVetted-geography-matters-with-blastomycosis>
 blastomycosis — or blasto, as it is often called. 

Blasto most commonly infects dogs, although other species, including cats and 
people, can be affected (but not through contact with infected dogs). The 
organism lives in moist, sandy, acidic soil that is rich in organ ic matter, 
which explains why the only case I’ve diagnosed since moving to the arid west 
was in a dog that lived part time near Lake Michigan. Blasto "hotspots" include 
Mississippi, Ohio, Missouri, Tennessee, the St. Lawrence River valley, the mid 
Atlantic states, and areas around the Great Lakes.

Dogs usually inhale Blastomyces spores from the soil, leading to infection of 
the lungs. Once established there, the organisms can travel anywhere in the 
body. Symptoms depend on where the infection localizes but some combination of 
poor appetite, weight loss, coughing, difficulty breathing, limping, eye 
problems, skin lesions (particularly around the toenails), enlarged lymph nodes 
and fever are common. If the organism infects the brain, seizures and other 
neurologic problems may also develop.

Diagnosing blastomycosis usually involves first eliminating other more common 
diseases through blood chemistry panels, complete blood cell counts, a 
urinalysis and X-ray s, and a rising index of suspicion based on those results.

For example, blasto-related pneumonia will often have a "snow storm" appearance 
on chest X-rays, which differs from the typical look of a bacterial or viral 
pneumonia. Serologic testing can help determine whether or not a dog has been 
exposed to blasto, but the results can be hard to interpret since early 
infections may be missed and positive results aren’t always associated with a 
current, active infection. Ideally, the diagnosis should be based on finding 
the organism on tissue or cytological samples taken by needle aspirate, smear, 
or biopsy.

When caught early enough in the course of the disease, blasto can often be 
effectively treated with anti-fungal medications, and symptomatic and 
supportive care. Itraconazole is the drug of choice, although other medications 
like fluconazole or amphotericin might be appropriate under certain 
circumstances. Blasto of the eye is especially difficult to eradicate becau se 
of the limited ability of anti-fungal medications to pass from the bloodstream 
into ocular structures

Treating fungal infections takes patience. Dogs with blasto may not begin to 
improve for a week or two after appropriate treatment has begun. Drug therapy 
often needs to be continued for many months to avoid relapses once treatment is 
stopped.

Veterinarians in blasto-endemic areas should be familiar with the disease and 
have it towards the top of their rule-out lists for dogs with characteristic 
symptoms. If, however, you have recently moved from or traveled to one of these 
areas and your dog gets sick, be sure to tell your vet. This information is 
critical if your dog is to benefit from a prompt and accurate diagnosis and 
avoid potentially life threatening delays in treatment.

 

 

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Dr. Jennifer Coates

 

 

Image: Charlie’s X-ray (to see the "snow storm" appearance in the full X-ray 
image,  
<http://www.petmd.com/sites/default/files/charlie_blasto_xray.JPG?utm_source=Newsletter&utm_medium=Email&utm_content=20120301&utm_campaign=FullyVetted-geography-matters-with-blastomycosis>
 click here), shared by Charlie’s owner, Bob, on  
<http://blastomycosis.ca/index.cgi?page=dog%20> blastomycosis.ca

 


 
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