Mailchannels (http://mailchannels.com/) comes to mind.  I don't have any
experience with it, but it would seem to meet your product requirments.

Frank

-----Original Message-----
From: [email protected]
[mailto:[email protected]] On Behalf Of Felix Nkansah
Sent: Wednesday, July 06, 2011 7:42 PM
To: [email protected]
Subject: [c-nsp] Service Provider Anti-Spam

Hello,

I am interested in deploying an anti-spam solution in an ISP network that
would scan all incoming/outgoing email traffic and block spam to/from
downstream users.

The system should be integrated to work in the ISP network without requiring
any subscriber (business or individual) to make changes on his
network/servers.

I would appreciate your suggestions on a good product/solution and/or
approach.

Thanks. Felix
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