Hi, I have the same problem on clamav with 0.91 and 0.91.1 version, in log 
file I have:

Jul 24 11:30:36 mail amavis[8184]: (08184-08) TROUBLE in check_mail: 
virus_scan FAILED: virus_scan: ALL VIRUS SCANNERS FAILED: ClamAV-clamscan 
av-scanner FAILED: /usr/bin/clamscan unexpected exit 50, output="LibClamAV 
Error: Can't load /var/lib/clamav/*.cvd: Broken or not a CVD file\nERROR: 
Broken or not a CVD file" at (eval 37) line 408.
Jul 24 11:30:36 mail amavis[8184]: (08184-08) PRESERVING EVIDENCE in 
/var/amavis/tmp/amavis-20070724T113036-08184
Jul 24 11:30:36 mail postfix/smtp[8319]: 5925450127A: 
to=<[EMAIL PROTECTED]>, relay=127.0.0.1[127.0.0.1], delay=0, status=deferred 
(host 127.0.0.1[127.0.0.1] said: 451-4.5.0 Error in processing, id=08184-08, 
virus_scan FAILED: virus_scan: ALL VIRUS SCANNERS FAILED: ClamAV-clamscan 
av-scanner FAILED: /usr/bin/clamscan unexpected exit 50, output="LibClamAV 
Error: Can't load /var/lib/clamav/*.cvd: Broken or not a CVD file 451 4.5.0 
ERROR: Broken or not a CVD file" at (eval 37) line 408. (in reply to end of 
DATA command)

..yesterday I have deleted the files:

/var/lib/clamav/*.cvd
/var/lib/clamav/mirrors.dat

..and in this mode I have solved my problem but in this morning I have even 
the same problem, I have deleted again:

/var/lib/clamav/*.cvd
/var/lib/clamav/mirrors.dat

..and the problema is solved but tomorrow ?? pheraps I must doing another 
operation ?
Thanks.

------
Salvatore.

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