Hi Teresa, It looks like we were dx around the same time.  Dr. Faderl 
said at this time he didn't think it was neccessary to increase the 
dose at this time.  He said you can keep acheiving results up to 42 
months into your treatment.  He said we would keep monitoring and as 
long as it was going down for now he thought I should stay on 400mg.  
I tolerate gleevec very well.  The side effects are manigable with 
lasix 40mg, magnesium, potassium, calcium.  The side effect that 
bothers me the most is the water retention.

Congratulations to you too.  I go back in June for my nect qpcr.  I'm 
hoping for pcru.  Good luck to you on all of you tests.

Shari from Kansas

-- In [email protected], <[EMAIL PROTECTED]> wrote:
> 
>   Shari, congratulation. Your results are the same as my, I was dxd 
in January 2003 and start 400mg Gleevec in February 20 , 03. I 
achieved CCR in July 03. My lfirst QPCR result in December 2004 was 
0.06. Dr. List at Moffit Center in Tampa told me during my January 
5th visit, that I am doing fine and to achieve faster results or PCRU 
is to increase Gleevec dosage. I am not excited about this news 
because of the water retention and other side effects I have been 
experienced. We are waiting for my next visit in March 30th to check 
again my PCR and to monitor my progress. Good Luck to you and I hope 
you achieve  PCRU soon or may be we both will at same time. Best
> 
>   Teresa T from Florida
> 
>   shari3059 <[EMAIL PROTECTED]> wrote:
> 
> 
>     Last night at 7:00 I received a phone call from Dr. Faderl 
himself, 
>     and that made me a little nervous.  I was expecting a call from 
his 
>     nurse.  I thought something must be wrong if he was making the 
call 
>     himself.  But all of my tests were either normal or negitive 
except 
>     my q-pcr results and I think he said it was 0.09.  He said that 
it 
>     was good and that there is still time for it to go down more.  
He 
>     said if it had been 0.05 that would be a major molecular 
response.  
>     So I really don't know how good this response is, but I have 
been 
>     taking 400mg for 2 years on feb. 18.  He thinks that I am doing 
>     great.  I go back to MDACC on june 8 for my next pcr.  Hoping 
to be 
>     pcru soon.
> 
>     Shari from Kansas
>     dx feb 10 2003
>     ccr june 12 2003
>     400mg gleevec
>     qpcr  0.09
> 
> 
> 
> 
> 
> 
> 
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