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Barbara,
Am I correct, that you are living in France, near
Lyons? My wife and I lived in the Bordeaux area of France for three
years....and traveled through your area many times. Just curious.
Thanks,
Jim Beck - Pennsylvania - USA
----- Original Message -----
Sent: Wednesday, February 02, 2005 12:03
PM
Subject: [CML] Re: Information on Trisomy
8
Hi Jim,
thanks for this information. My
trisomy 8 is in my ph neg cells and
apparently it's not as significant as
trisomy 8 in ph positive
cells. I'll be seeing my doctor next
Wednesday & I've got loads of
questions to ask him, so I'll let you
know what he says. Quite a
few people who've had this abnormality
have later seen it disappear -
so it's something to keep a close eye
on,
thanks again,
Barbara--- In [email protected], "James Beck"
<[EMAIL PROTECTED]>
wrote:
> Hi To All,
> Here is some
information that I found while searching on Google.
I searched the
word Trisomy 8...and this was the result. Hope this
helps.
>
> Regards,
> Jim Beck -
PA
> dx 8/2001
> gleevec 600mg
>
> +8 or trisomy
8
> Clinics and Pathology
>
>
> Disease chronic
myelogenous leukaemia (CML)
>
Epidemiology +8 is one of the major anomalies additional to
the t(9;22),
with i(17q), + der(22), before +19; found as a unique
additional anomaly
in 10%, with other in 25% of CML cases with
clonal evolution; these
additional anomalies may be present at the
diagnosis of CML (in 10%,
possibly with unfavourable significance),
or may appear during course of
the disease, they do not indicate the
imminence of a blast crisis,
although they also frequently emerge at
the time of acute transformation;
+8 is more often found in the
myeloid than in the lymphoid blast crisis.
> Prognosis +8 has apparently no
prognostic significance in
CML
>
>
> Check the site
shown below....seems to have a lot of other
information...
> ( looks
like a site originating from France)
>
> Web Site -
http://www.infobiogen.fr/services/chromcancer/Anomalies/tri8ID1017.ht
ml
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