---------- Forwarded message ----------
From: Rob <[email protected]>
Date: Tue, 15 Feb 2005 22:31:11 -0600
Subject: [CMLHope] Synthetic, spectral, magnetic and in vitro
cytotoxic activity studies of cobalt(II) complexes with cytokinin
derivatives: X-ray structure of 6-(3-methoxybenzylamino)purinium
chloride monohydrate.
To: [EMAIL PROTECTED]


Cobalt(II) complexes with 6-(2-hydroxybenzylamino)purine (HL(1)),
6-(2-methoxybenzylamino)purine (HL(2)), 6-(3-methoxybenzylamino)purine
(HL(3)) and 6-(4-methoxybenzylamino)purine (HL(4)) of the composition
[Co(L(1))Cl(H(2)O)(2)].H(2)O (1), [Co(L(2))Cl(H(2)O)(2)] (2),
[Co(L(3))(2)(H(2)O)(2)].2H(2)O (3), [Co(L(4))(2)(H(2)O)(2)].2H(2)O (4)
have been synthesized. The compounds have been characterized by
elemental analysis, FT-IR, ES+ MS (electrospray mass spectra in the
positive ion mode) and electronic spectroscopies, magnetic and
conductivity data as tetrahedral high-spin cobalt(II) complexes. The
thermal stability of the complexes has also been studied. The
cytotoxicity of the complexes (1-4) was determined by a Calcein
acetoxymethyl (AM) assay. Human malignant melanoma (G361), human
chronic myelogenous erythroleukemia (K562), human osteogenic sarcoma
(HOS) and human breast adenocarcinoma (MCF7) cell lines were used for
the testing.
 
http://cmlsupport.blogspot.com/2005/02/synthetic-spectral-magnetic-and-in.html


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