--- In [email protected], <[EMAIL PROTECTED]> wrote: 
> A short time later, while laying on a gurney in the hallway, I got 
the bad
> news that my White Blood Cell count was very high, and that it 
indicated I
> had Leukemia.  My WBC count at that time was 386,000.  (I still 
don't know
> what the units of that measurement are - I guess it means that many 
white
> blood cells in some volume of blood)  They also told me that I would 
be
> admitted to the hospital - so they wheeled me into the actual 
Emergency Room
> and started me on an I.V. antibiotic - this must have been better 
medicine
> than the previous antibiotics I had been prescribed by my regular 
doctor,
> because I started feeling better pretty soon.  By Saturday during 
the day, I
> actually felt better than I had in a couple of weeks.
> 
> I was in the hospital over the weekend, only getting more of the 
antibiotic
> (I think it was called Levoquin) - because the oncologist at the 
hospital
> would not be there to see me until Monday.  By then, after many more 
blood
> tests, the oncologist made a preliminary diagnosis that I had CML.  
But he
> ordered a bone marrow biopsy to be sure.  I had the procedure to 
remove a
> bone marrow sample on Tuesday morning, and was released from the 
hospital
> the next day.  The oncologist had told me that he would prescribe a 
new drug
> for me - called Gleevec.
_____ 
> The real surprise, though, for both me and the doctor was my WBC 
count.  It
> was down to 1.4.  He seemed a little bit surprised that it was so 
low, and
> of course told me to temporarily discontinue taking the Gleevec.  My 
other
> counts - RBC and platelets were good, though.  But I will go back 


> Pat Sharp
> Perris, California

________________

Hi Pat,

Where is Perris, Calif? I used to live in Santa Barbara, also in Long 
Beach.....but now I am in Oregon. Mainly I was wondering if you were 
anywhere near a larger cancer center where you might see a cml 
specialist. 

Also, this list is almost defunct....not much posting. So, I suppose 
you should switch to the other List and maybe Rob will tell you how to 
do that, unless your message is automatically going there also???

Sorry you had such a tough time getting diagnosed.....and that no one 
did a simple blood test earlier. Other do have similar stories but a 
simple blood test would have given them answers when you first got 
sick. 

Normal white count is 5-10,000..........so your count was pretty high 
and causing the problems. Some doctors would have given you another 
drug, hydrea, first to get your white count down. But it is typical 
with Gleevec (also referred to as IM) to get back to normal blood 
counts in 4-8 weeks. You should not be off IM long....it would be 
preferable to be on the lower starting dose of 400mg than to be off 
the drug. It is OK if the white count drops to 2-4.......what you need 
for protection against infections, etc. is an absolute neutrophil 
count of 1.0. Neutrophils are a certain % of your total white count, 
and you might see what % it is on your blood test. 

I will tell you that when you had a white count of 167,000....most 
specialist would not let you be on your own with regular blood tests 
for a month (I think you wrote this). I would ask your oncologist how 
many patients he has on Gleevec....if his experience is limited, you 
might suggest that he gets a 2nd opinion on decisions. 

You have had a good response to Gleevec, which is good. You don't 
mention is your platelets were in the normal range at diagnosis, or if 
they were also elevated. 

PS I think your regular physician did a poor job (not even getting a 
blood test) even if it was flu season! He should be thinking twice 
about how he deals with ill people from now on. 

Nancy C. 
on Gleevec since 2-2000, so lots of experience





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