I too have slightly elevated creatinine levels. My oncologist did not seem concerned but I was so I went to my regular doctor who consulted with his partner, who happened to be a specialist in nephrology- kidneys that is - and then referred me to him. The kidney specialist ordered blood work, ultrasound, and a 24-urine sample. I have creatinine levels of between 1.2 and 1.4, which are borderline and have had these levels - at least - since diagnosis in June 2004.
I am taking Gleevec but it is not the cause of the elevated creatinine as I have blood work that shows that I had creatinine levels on the high end of normal before I started on Gleevec. I received the test results earlier this week and met with the doctor. All the tests came out fine. The specialist told me not to worry and said that people who are very muscular or work out a lot tend to have higher creatinine levels. Creatinine is a byproduct of muscle breakdown. The better test is not the serum (blood) creatinine level but the 24hr urine creatinine clearance, which measures how much creatinine your kidney processes. For most people, a high level of creatinine in the blood means that the kidneys are impaired and therefore not clearing out the creatinine and thus a higher level backs up in the blood. Those who work out intensely have higher levels of creatinine in the blood than a normal person. Maybe there is a connection between higher levels of creatinine production and leukemia but that is only my theory at this point. PS: Regarding the repeated posts issue....I am not criticizing Rob but I wanted to weigh in here on repeated posting with bad links, limited text, etc. I really would appreciate less "posting" and more primary information. I am only guessing but I think that it is not a small minority that feel this way but a silent majority. I don't need more information about small Gleevec studies or press releases by start-up drug companies. There are already many published studies regarding Gleevec, Gleevec and relapse curves, Gleevec and optimal dosage, etc. in major respected journals and magazines that we don't have to go grabbing at every little tid bit of information as if we were starving. At this point I think we have the luxury of being selective in what we post - a good thing! --- In [email protected], nancy wilhelm <[EMAIL PROTECTED]> wrote: > Hello, Chris, > My husband, Bob, is on the BMS drug and has high Creatinine readings, too. So it's probably not the Gleevec. His has been as high as 1.8, but is usually around 1.5 or 1.6. He recently had a stone removed from the bile duct, but his creatinine still stayed high, although the Alkaline Phosphatase went down considerably. Just to let you know you are not the only one with a creatinine "problem". Hang in there! > blessed be nancy w inyokern ca > > stick924 <[EMAIL PROTECTED]> wrote: > > > Richard and all, > > > Thanks for the responses you provided in late January. I had two > Serum Creatinine readings (1 week apart) where my results were > elevated. 1.5 on the first reading and 1.8 the second. A "kidney > specialist" had me tested 4 ways to Sunday and then I had to wait > for 3 weeks to get results. Bottom line - readings were back to my > baseline of 1.4 - high but in range. > > Bottom line - Dr said don't exercise vigorously in the days before > blood tests and always drink a lot of water when you do. I am back > to Hoops tomorrow! Dont know if Gleevex causes this phenomena but > wanted to let other folks be aware. > > All, the best! > > Chris > > > > > > > > > New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com > > Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com > > CML (Chronic Myelogenous Leukemia Support List) > --------------------------------- > Part Of CMLHope.Com > An International Community Of CML Patients > For more information: http://cmlhope.com > > Post Message: [email protected] > Subscribe: [EMAIL PROTECTED] > Unsubscribe: [EMAIL PROTECTED] > Change To No Mail/Web: [EMAIL PROTECTED] > Change To Digest: [EMAIL PROTECTED] > Change To Email: [EMAIL PROTECTED] > List Help: [EMAIL PROTECTED] > CML Group Web Site http://groups.yahoo.com/group/CML > > > > Yahoo! Groups SponsorADVERTISEMENT > > > --------------------------------- > Yahoo! Groups Links > > To visit your group on the web, go to: > http://groups.yahoo.com/group/CML/ > > To unsubscribe from this group, send an email to: > [EMAIL PROTECTED] > > Your use of Yahoo! Groups is subject to the Yahoo! Terms of Service. ------------------------ Yahoo! Groups Sponsor --------------------~--> Ever feel sad or cry for no reason at all? Depression. Narrated by Kate Hudson. http://us.click.yahoo.com/1visLB/esnJAA/xGEGAA/8zSolB/TM --------------------------------------------------------------------~-> New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com CML (Chronic Myelogenous Leukemia Support List) --------------------------------- Part Of CMLHope.Com An International Community Of CML Patients For more information: http://cmlhope.com Post Message: [email protected] Subscribe: [EMAIL PROTECTED] Unsubscribe: [EMAIL PROTECTED] Change To No Mail/Web: [EMAIL PROTECTED] Change To Digest: [EMAIL PROTECTED] Change To Email: [EMAIL PROTECTED] List Help: [EMAIL PROTECTED] CML Group Web Site http://groups.yahoo.com/group/CML Yahoo! 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