The Clinical Advisory Board will also advise Onconova on other drug candidates being developed by the Company. These include ON 01210, Ex-RAD(TM), for protection from whole-body radiation, being developed in partnership with the Armed Forces Radiobiology Research Institute (AFRRI); an advanced preclinical stage compound targeting BCR-ABL involved in Chronic Myelogenous Leukemia (CML). A key attribute of this inhibitor is its potent activity against all mutant forms of BCR-ABL kinase found in drug-resistant CML. The Company also has a strong pipeline of specific enzyme inhibitors, applicable for cancer, autoimmune, ophthalmic, and central nervous system indications, in earlier stages of development.


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