---------- Forwarded message ----------

   Arch Dermatol. 2005  Mar;141(3):368-70. _Related  Articles,_
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Display&dopt=pubmed_pubmed&fro
m_uid=15781678&tool=ExternalSearch)  _Links_
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(http://www.ncbi.nlm.nih.gov/entrez/utils/lofref.fcgi?PrId=3051&uid=15781678&db=PubMed&url=http://archderm.ama-assn.org/cgi/pmidlookup?view=long&pmid=15781
678)
Imatinib-induced sweet syndrome  in a patient with chronic myeloid leukemia.

Ayirookuzhi SJ,  Ma L, Ramshesh P, Mills G.

Department of Medicine, Louisiana State  University Health Sciences Center at
Shreveport, Shreveport, LA 71130, USA.  [EMAIL PROTECTED]

BACKGROUND: Imatinib mesylate has become one of  the main chemotherapeutic
agents currently used to treat patients with chronic  myeloid leukemia (CML).
Although cutaneous reactions to this drug have been  documented before, this is
the first time that Sweet syndrome has been reported  with its use.
OBSERVATIONS: We report a case of Sweet syndrome secondary to the 
administration of
imatinib to treat CML. On 2 separate occasions, a 53-year-old  African American
woman with CML developed neutrophilic dermatosis consistent  with Sweet
syndrome after chemotherapy with imatinib. CONCLUSION: Greater  awareness of the
adverse effects of imatinib and the characterization of its  cutaneous adverse
effects will lead to improved surveillance for and treatment  of those adverse
effects.

PMID: 15781678 [PubMed - in process]


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