---------- Forwarded message ----------

DNA DAMAGE IN CANCER SOONER THAN THOUGHT

University of Liverpool scientists have developed ways of
detecting areas of instability in DNA known to lead to the
development of cancer. The research, published in Nature,
demonstrates that breaks occur at fragile sites of cells'
DNA very early in the carcinogenic process. The DNA breaks
are produced by abnormalities in the cell division process
that are caused by carcinogens such as tobacco smoke. The
DNA damage occurs very early in the development of pre-
cancerous cells and could highlight those at risk of
developing cancer at a much earlier stage than current
screening processes allow, according to Dr. Lakis Liloglou,
head of the University's Lung Cancer Molecular Biomarkers
Group.


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