Hi Dane, I am so sorry to hear of your setback. Hopefully is will only be a pebble on your path to cure.
My appointment at MDA is on 6/2. Hopefully for you you will be home by then. If not, maybe we can meet. Judy L > Message: 9 > Date: Mon, 25 Apr 2005 16:24:42 -0500 > From: "Dane" <[EMAIL PROTECTED]> > Subject: 76 Days Post BMT----First Setback > > Day 76 brings my first setback since the BMT process began. > > I received the results of my second biopsy today. It showed that I am now > 100% donor cells (good) but my BCR-ABL level is up to 13.5 (not good). > > In comparison, my first biopsy came back 99% donor cells and a BCR-ABL level > of 1.0. > > Dr. DeLima explained to me that the anti-GVHD drug tacrolimus also reduces the > donor cells' ability to fight the leukemia, so now my tacrolimus dose will be > decreased. > > The plan is to induce a small amount of GVHD in order to achieve Graft Vs > Leukemia. Graft Vs Leukemia can start to bring the BCR-ABL level back down. > > Dr. DeLima has also mentioned the possibility of bringing Gleevec back into > the mix, but I have my doubts about this because I have already shown a > resistance to the drug. I talked with him as well as with my research onc > about replacing the use of Gleevec with one of the newer BMS or AMN107 drugs > to knock out the BCR-ABL and give my new immune system a helping hand. > > He thought enough of the idea to email my research onc to get his opinion. I > sent my research onc a similar email and expect to hear back from him soon. > > In the meantime, any chance of going home early is now gone, as my test > results were not optimum. I will be here for at least another month, possibly > longer. The good news is that as of this writing, I should still be allowed > to go home on weekends. > > As of this writing, I am still only in clinic two days a week, and I am still > off home infusions unless my magnesium levels drop lower than they are. > > So I wait....three more weeks until another biopsy, one more week to get those > results. > > Tick....tock.....tick....tock, etc. > > Not the best day I've had since this thing began. > > Dane > ------------------------ Yahoo! Groups Sponsor --------------------~--> Does he tell you he loves you when he's hitting you? Abuse. Narrated by Halle Berry. http://us.click.yahoo.com/AoisKB/isnJAA/xGEGAA/8zSolB/TM --------------------------------------------------------------------~-> New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com CML (Chronic Myelogenous Leukemia Support List) --------------------------------- Part Of CMLHope.Com An International Community Of CML Patients For more information: http://cmlhope.com Post Message: [email protected] Subscribe: [EMAIL PROTECTED] Unsubscribe: [EMAIL PROTECTED] Change To No Mail/Web: [EMAIL PROTECTED] Change To Digest: [EMAIL PROTECTED] Change To Email: [EMAIL PROTECTED] List Help: [EMAIL PROTECTED] CML Group Web Site http://groups.yahoo.com/group/CML Yahoo! Groups Links <*> To visit your group on the web, go to: http://groups.yahoo.com/group/CML/ <*> To unsubscribe from this group, send an email to: [EMAIL PROTECTED] <*> Your use of Yahoo! Groups is subject to: http://docs.yahoo.com/info/terms/
