A new experimental drug may be effective against a certain form of leukemia resistant to current treatments, research at UT Southwestern Medical Center shows...The Blood study shows that PD166326 is nearly 100 times more potent than the current drug imatinib (Gleevec) against cells expressing this enzyme, Dr. Ilaria said...When mice received a single oral dose of PD166326, the mutated enzyme activity was rapidly inhibited, and the white blood count significantly decreased.
 


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