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Novartis' Gleevec works wonders for people suffering from chronic
myelogenous leukemia, or CML, which causes certain white blood cells to
proliferate uncontrollably. But eventually many patients become resistant to the
drug. In an early trial conducted at UCLA and M.D. Andersons, Bristol's 354825
compound, however, was able to normalize white blood cell counts in 31 of 36
leukemia patients who had failed or could not tolerate Gleevec.
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