|
In this study, we report the case of a Philadelphia (Ph) positive chronic
myelogenous leukemia (CML) patient with the presence of p190 and p210 BCR-ABL1
mRNA fusion transcripts derived from e1a2 and b3a2 BCR-ABL1 genomic
rearrangements, respectively. The presence of e1a2 BCR-ABL1 genomic
rearrangement was seen in 2 different clones, one with the rearrangement and
another one with the rearrangement and deletion of the BCR gene of the
non-rearranged chromosome 22. After treatment with imatinib, the p210 transcript
could not be detected, whereas p190 was still present 6 months after initiation
of imatinib therapy and progression to blast phase.
New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com CML (Chronic Myelogenous Leukemia Support List) --------------------------------- Part Of CMLHope.Com An International Community Of CML Patients For more information: http://cmlhope.com Post Message: [email protected] Subscribe: [EMAIL PROTECTED] Unsubscribe: [EMAIL PROTECTED] Change To No Mail/Web: [EMAIL PROTECTED] Change To Digest: [EMAIL PROTECTED] Change To Email: [EMAIL PROTECTED] List Help: [EMAIL PROTECTED] CML Group Web Site http://groups.yahoo.com/group/CML Yahoo! Groups Links
|
