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In the past 10 years, progress made in cancer biology, genetics, and
biotechnology has led to a major transition in cancer drug design and
development. There has been a change from an emphasis on non-specific, cytotoxic
agents to specific, molecular-based therapeutics.Mechanism-based therapy is
designed to act on cellular and molecular targets that are causally involved in
the formation, growth, and progression of human cancers.
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