I remember someone asking about Gleevec before transplant. I couldn't remember which group posted the question, so I am posting this information to all groups, excuse the repetition. This is an article specifically about CML and stem cell transplants. There is also discussion about taking Gleevec prior to transplant. The advice given is to stop Gleevec usage 30 days prior to transplant because of liver toxicity. Wish I would've read this sooner.
Here is a brief snippet of the article and the website:
<x-tad-bigger>Conference Coverage</x-tad-bigger>
Stem Cell Transplants for Chronic Myeloid Leukemia (CML) EBMT 2004
Date: March 28-31, 2004
Location: Barcelona, Spain
Author: C. D. Buckner, MD
<x-tad-bigger>
Introduction</x-tad-bigger>
The European Group for Bone Marrow Transplantation (EBMT) held the 30th annual meeting in Barcelona from March 28-31 2004. At this meeting there were several presentations about the outcomes of patients receiving allogeneic stem cell transplants for CML. All the transplant centers have observed a 50% or greater reduction in the number of patients transplanted for CML in the chronic phase since the introduction of Gleevec® in 2000. Dr. John Goldman of Hammersmith Hospital, who is considered to be the world’s experts on CML, delivered an opening address outlining the status of allogeneic stem cell transplantation in the Gleevec® era.
http://professional.cancerconsultants.com/conference_ebmt_2004.aspx?id=30036
Barb Neddo,
Mom to Tom,
dx CML 8/04, MUD BMT 05/05/05
http://www.caringbridge.org/wi/tomneddo
