Guys,
I've not been in touch in a long time but I've read this list since 1999.  I'll offer a bit of a re-introduction, since I know the members have changed and the membership has grown.  I always tell people about the list, but hesitate to participate.  I work a lot and don't like to feel like I can't keep up with everything here - and would hate to not respond to someone when I need to.  I will say, please let me know if you need anything from me - and don't hesitate to send a reminder should I not respond (I do think my memory is very bad - and I'm more than content to blame it on the drugs).  At any rate, I'm now 38 - diagnosed at 32 - a year on Ara-C and Interferon - and then the STI Phase II trial at OHSU.  I still see Dr. Druker every six months.  I've been on Gleevec since June 26 of 2000.   I now take 600mg daily and I've kind of ping-ponged around in responses.  My FISH has always remained positive, thought I've had negative or undetectable PCR results at times.   I  used to worry far more than I do now - as I'm becoming a fairly predictable  patient - though my results are back and forth (detectable - undetectable) I'm very stable.  My WBC is always low; my anemia worsens and improves, but never goes away; my eyes are chronically puffy; and I'm always cold and wish I had more energy.  While that may sound pitiful, I'm extremely satisfied.  I'm very excited about the new drugs in development and can testify to the difference between then and now.  I will never forget the horrible chemo/interferon days - when I was so very sick and enduring the terrible side effects of medicine that wasn't fighting the disease.  I know what a difference this drug made for me - as it truly did save my life.  I'm not a content person, but I'm very happy.
 
Through my "journey" I've known so many not nearly as fortunate.  I've had friends who have died when Gleevec didn't work for them.  I've also had friends with extremely positive transplant results.  My advice to anyone is to "follow your gut - be educated and open, and the right decision will reveal itself."  My beliefs are based in my spirituality, I guess - but I also believe that we each have to decide what our correct path is.  Transplant was not for me -but that doesn't mean that it won't be in the future. 
 
For anyone that may be interested, I'm in serious contemplation about trying to conceive on Gleevec and have yet to make a decision.  My age and my previous treatment are obvious complications to the dilemma - but I'm hoping I'll know what's right sooner rather than later. 
 
Finally, Kelly Ann - your post inspired me to write.  I'm also in Tennessee and would be happy to offer any contacts, info, etc. that you might like to have.   I'll send my phone number off-list and you can call or email if you like.  The same is true for anyone here.    
 
Please take care and know that you all are thought of and cared about by many whom you may never know.
Paige Brown Strong


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