In phase II trials, 90% of patients receiving dastinib showed normal blood cell counts within six months. Of the 186 patients, 54% had been taking Gleevec for more than three years and either failed to respond to the maximum dose or developed drug-resistant versions of the disease.

Despite only a six-month follow up, a significant response to dasatinib was seen in all phases of the disease, says Dr. Andreas Hocchaus, a trial investigator at the University of Heidelberg in Germany.
 


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