A fresh look at the delicate dance of enzymes within living cells has provided insights into how one genetic mutation can lead to three distinct blood disorders.
The discovery ?provides new and important insights into how this gene contributes to the development of myeloproliferative disease,? said D. Gary Gilliland, a Howard Hughes Medical Institute researcher at Brigham and Women's Hospital and Harvard Medical School. ?It should provide an important foundation for subsequent development of new drugs,? he added.
?Although relatively rare individually, together these disorders are about five times more common than chronic myelogenous leukemia.?
D. Gary Gilliland
The new research results, found in collaboration with biologist Harvey Lodish's team at the Whitehead Institute for Biomedical Research, were announced December 19, 2005, in an immediate early online publication in the Proceedings of the National Academy of Sciences.
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Posted by Rob to CML Newswire: Medical And Technical News On Chronic Myelogenous Leukemia at 12/19/2005 11:05:20 PM
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