Rezvani K, Brenchley JM, Price DA, Kilical Y, Gostick E, Sewell AK, Li J, Mielke S, Douek DC, Barrett AJ
Clin Cancer Res. 2005 Dec 15; 11(24): 8799-8807

PURPOSE: Antigens derived from the Wilms' tumor (WT1) protein, which is overexpressed in leukemias, are attractive targets for immunotherapy. Four HLA-A*0201-restricted WT1-derived epitopes have been identified: WT37, WT126, WT187, and WT235. We determined the natural immunogenecity of these antigens in patients with hematologic malignancies and healthy donor.

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Posted by Rob to CML Newswire: Medical And Technical News On Chronic Myelogenous Leukemia at 12/22/2005 02:09:21 AM


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