Hi, my husband was has been on gleevec since August of 2005 and is also 400mg and  has adjusted to the gleeve fine, however if he does not drink LOTS and LOTS of water the same thing happens to him he gets bad muscle cramps and many other side effects.  I hope this little information helps.Anl
----- Original Message -----
From: Wild Kat
Sent: Tuesday, January 03, 2006 10:17 AM
Subject: [CML] Side Effects

Hello. I'm new to the group and have a question about the side effects of
Gleevec. I've noticed that when I try and run for exercise now, my calves
cramp up fairly badly after about a mile. I used to run 6-8 miles a day but
now it seems like the most I can manage is 2 and half the time I walk home
after the first one. I've been on 400mg gleevec for about 6 weeks now. I've
tried extra stretching and more potassium in my diet but so far nothing
helps and I'm getting fairly frustrated. Does anyone have any ideas that
might help? I was hoping to run in a local race in March but at this rate...
Thanks for any ideas.  Cheers,  Kat C.

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