This is what I found at http://www.cancerbacup.org.uk/Cancertype/Leukaemiachronicmyeloid/ Causesdiagnosis/Diagnosis
Philadelphia chromosome Most people with CML have a genetic abnormality known as a Philadelphia chromosome which can be detected by laboratory tests. Every cell in the body has a nucleus that contains chromosomes. Chromosomes are long structures made up of DNA. DNA determines how the cell looks and acts. The Philadelphia chromosome develops when part of chromosome 9 (the ABL gene) wrongly attaches to chromosome 22 (the BCR gene) during cell division. This creates a new gene, known as BCR-ABL which produces a specific new protein. The protein causes the production of an enzyme called tyrosine kinase, which leads to the chronic phase of CML by stimulating the production of abnormal blood cells by the bone marrow. The Philadelphia chromosome is not inherited and cannot be passed on to your children. The email for ER is [EMAIL PROTECTED] Barb http://www.caringbridge.org/wi/tomneddo ------------------------ Yahoo! Groups Sponsor --------------------~--> AIDS has a woman's face. Help women to protect themselves. http://us.click.yahoo.com/VHwV5B/TREMAA/xGEGAA/8zSolB/TM --------------------------------------------------------------------~-> New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com CML (Chronic Myelogenous Leukemia Support List) --------------------------------- Part Of CMLHope.Com An International Community Of CML Patients For more information: http://cmlhope.com Post Message: [email protected] Subscribe: [EMAIL PROTECTED] Unsubscribe: [EMAIL PROTECTED] Change To No Mail/Web: [EMAIL PROTECTED] Change To Digest: [EMAIL PROTECTED] Change To Email: [EMAIL PROTECTED] List Help: [EMAIL PROTECTED] CML Group Web Site http://groups.yahoo.com/group/CML Yahoo! Groups Links <*> To visit your group on the web, go to: http://groups.yahoo.com/group/CML/ <*> To unsubscribe from this group, send an email to: [EMAIL PROTECTED] <*> Your use of Yahoo! Groups is subject to: http://docs.yahoo.com/info/terms/
