Hi Amit,

  Your Dad's blood count does not show any blasts and neither does his
marrow, so I do not think he is in blast crisis.  Your Dad's Hemoglobin
count is very low and so is his red blood cell count.  So, the doctor
is doing the Coomb's test to find out why the red blood cell count is
so low and why he is having anemia.  Antibodies are proteins from the
immune system that attack foreign invaders to the body.  Sometimes,
antibodies can attack the patient's own cells and this is called
autoimmune disease.  A patient can have autoimmune anemia where the
antibodies attack and destroy the body's own red blood cells.  Coomb's
test finds out whether your Dad's red blood cells are being destroyed
by antibodies, see the link below.

http://www.healthatoz.com/healthatoz/Atoz/ency/coombs_tests.jsp

  The doctor wants to see why your Dad's red blood cells are getting
destroyed and this test will help him find the reason.  Let us know the
results.

Best Wishes,
Anjana


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