Hi Amit,

  I am sorry that your Dad is in blast crisis.  Low counts are common
in blast crisis.  600mg is the standard dose in blast crisis.  However,
updated trial results have shown that remissions if achieved with any
dose of Gleevec is not sustained well in blast crisis.  Singapore still
has the AMN107 trial open, 3 Indian patients are joining the trial in
the next few weeks.  AMN107 is a stronger drug than Gleevec and it is
in Phase II trials.  One of these patients coming is from AIIMS.
Discuss with your doctor this trial and see if it is a possibility for
your Dad.  If you are interested, write to me, privately, and I will
connect you to the Principal Investigator of the trial who is also my
husband's doctor.

Best Wishes,
Anjana
caregiver to Roy


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