I take my dosage of 400mg close to bedtime with a small snack - that
seems to help me with my vomiting/nausea.  I've was diagnosed and on
Gleevec since 5/2001.
Good Luck.

On Dec 14, 4:48 pm, grp4me <[EMAIL PROTECTED]> wrote:
> My husband was diagnosed with CML in Aug 2006 and has been on 400mg of
> Gleevec since diagnosis.  He has had intermittent problems with nausea
> and vomiting since he started.  However, in the past two weeks, he has
> had 3 instances of vomiting approx an hour after taking Gleevec.
>
> He already "sandwiches" his pill with food and lots of water and he
> takes Compazine about an hour before eating and taking Gleevec.
> Yesterday, his oncologist suggested Reglan instead of Compazine;
> however, he vomited again today so Reglan doesn't appear to be
> effective.
>
> Any suggestions from your experience?  We are in an excellent support
> group and CMLHope was suggested by several of its members.
>
> Thanks!
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