Relapse occurs in approximately 10 - 20 percent of patients transplanted during the chronic stage of CML, and a higher percentage of patients transplanted in later stages. As Julie indicated, generally the first thing the docs should try is a Donor Leukocyte Infusion (more blood cells from the sibling who was the original donor), and of course, Gleevec, Sprycel, or Tasigna. If the DLI does not work, then drug therapy will likely be the regimen. If the patient has no response to drug therapy, a second BMT from another donor could be done, or a clinical trial for investigational drugs or therapies could be an option. --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com -------------------------------------------------
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