Hi my friends, So my PCR came back at 0.4/1000 copies. My doctor said that it is a very stable result, but this time it did not drop. He said that this was my second PCR on the trial (Gleevec+Interferon+Sargamostim combo). I was said because my first PCR came at 0.2/1000, so I kind of was hoping to see PCRU, but no. My doctor – Dr. Smith from JHU said that it is very normal, that this is what they see, so I just need to give it a time and be patient. I was a little bit sad, but then I said to myself that I have really been on this combo only for 5 months and I need to stay on it for at least 10 – 12 months, so I just need to wait and see what the future PCRs will show. My side effects are manageable, but I must admit that since I started the trial, I am very tired. Sometimes I come home and do nothing. I watch TV and if I don’t fall asleep, I study for my class – boy I am so behind. I am only 30 years old!!! Hope everybody is doing fine! Livia dx February 2005
--- On Mon, 8/11/08, Trey <[EMAIL PROTECTED]> wrote: From: Trey <[EMAIL PROTECTED]> Subject: [CMLHope] Re: can someone comment on my cbc report thanks To: "CMLHope" <[email protected]> Date: Monday, August 11, 2008, 6:54 PM Generally, as you have noted, you have slightly high WBCs, which are mainly due to a high neutrophil count (neutrophilia). Since you have increased Gleevec dosage to 600mg somewhat recently as I recall, you could expect some CBC issues, but normally you would expect the WBC to drop, not increase. You show signs of anemia (low HGB and HCT), even though RBC is normal. The high neutrophil count could be caused by an infection, injury, kidney problems or other issues, so you should not rule those out. If you cannot recall recent infections or injury, I would encourage you to ask the docs to figure this out by doing some testing. Your WBC is just slightly high, but it can also be a sign of Gleevec resistence when WBC steadily rises, especially after increasing the Gleevec dosage, and coupled with your recent platelet issues it deserves attention. I could not find your latest PCR, FISH and BMB info here -- what is your recent history for these tests? You might want to discuss with your Onc having a PCR and also a BCR-ABL Mutation Test (aka, Gleevec Resistence Test). Here is one lab's description of the latter test (there are also other labs that do it): http://www.aruplab.com/guides/ug/tests/0040138.jsp --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [EMAIL PROTECTED] For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---
