If the increases are less than 1 log (for example from .007 to .07 is a 1 log increase), then Oncs do not normally tend to suggest a change. If the increases are miniscule, then there is no cause to be overly concerned.
Was a Gleevec "resistance test" done to determine why Gleevec stopped working? If not, you could ask your Onc about performing such a test. Here is one lab's description of it: http://www.aruplab.com/TestDirectory/resources/TechnicalBulletins/BCR-ABL1%20Kinase%20Domain%20Mutation%20Jan%202007.pdf Regarding your stem cell harvest and transplant/GVHD, I assume you mean that his own stem cells were harvested. If so, there is no GVHD with a re-infusion of one's own cells, since your body cannot reject your own cells. But this type of transplant is not for a cure, but rather is only used if the CML progresses into blast phase and other transplants are not feasible. But anyway, it is premature to be so concerned about that since you say the increases are miniscule. --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [EMAIL PROTECTED] For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---

