Hi all, Since I have high potassium in my blood, I thought this could be the problem. My onc would not even address this, and shouldn't he have known this could be caused by this? Anyone had this problem? Thanks to all. Jeanie<3 Tumor lysis syndrome >From Wikipedia, the free encyclopedia
Jump to: _navigation_ (http://en.wikipedia.org/wiki/Tumor_lysis_syndrome#column-one) , _search_ (http://en.wikipedia.org/wiki/Tumor_lysis_syndrome#searchInput) Tumor lysis syndrome Classification and external resources _DiseasesDB_ (http://en.wikipedia.org/wiki/Diseases_Database) _32051_ (http://www.diseasesdatabase.com/ddb32051.htm) _eMedicine_ (http://en.wikipedia.org/wiki/EMedicine) _med/2327_ (http://www.emedicine.com/med/topic2327.htm) _MeSH_ (http://en.wikipedia.org/wiki/Medical_Subject_Headings) _D015275_ (http://www.nlm.nih.gov/cgi/mesh/2008/MB_cgi?field=uid&term=D015275) In _medicine_ (http://en.wikipedia.org/wiki/Medicine) (_oncology_ (http://en.wikipedia.org/wiki/Oncology) and _hematology_ (http://en.wikipedia.org/wiki/Hematology) ), tumor lysis syndrome (TLS) is a group of _metabolic_ (http://en.wikipedia.org/wiki/Metabolism) complications that can occur after treatment of _cancer_ (http://en.wikipedia.org/wiki/Cancer) , usually _lymphomas_ (http://en.wikipedia.org/wiki/Lymphoma) and _leukemias_ (http://en.wikipedia.org/wiki/Leukemia) , and sometimes even without treatment. These complications are caused by the break-down products of dying cancer cells and include _hyperkalemia_ (http://en.wikipedia.org/wiki/Hyperkalemia) , _hyperphosphatemia_ (http://en.wikipedia.org/wiki/Hyperphosphatemia) , _hyperuricemia_ (http://en.wikipedia.org/wiki/Hyperuricemia) , _hypocalcemia_ (http://en.wikipedia.org/wiki/Hypocalcemia) , and _acute renal failure_ (http://en.wikipedia.org/wiki/Acute_renal_failure) . Contents [_hide_ (javascript:toggleToc()) ] * _1 Cause and risk factors_ (http://en.wikipedia.org/wiki/Tumor_lysis_syndrome#Cause_and_risk_factors) * _2 Symptoms and pathogenesis_ (http://en.wikipedia.org/wiki/Tumor_lysis_syndrome#Symptoms_and_pathogenesis) * _3 Diagnosis_ (http://en.wikipedia.org/wiki/Tumor_lysis_syndrome#Diagnosis) * _3.1 Cairo-Bishop Definition_ (http://en.wikipedia.org/wiki/Tumor_lysis_syndrome#Cairo-Bishop_Definition) * _4 Prevention_ (http://en.wikipedia.org/wiki/Tumor_lysis_syndrome#Prevention) * _5 Treatment_ (http://en.wikipedia.org/wiki/Tumor_lysis_syndrome#Treatment) * _6 References_ (http://en.wikipedia.org/wiki/Tumor_lysis_syndrome#References) [_edit_ (http://en.wikipedia.org/w/index.php?title=Tumor_lysis_syndrome&action=edit§ion=1) ] Cause and risk factors The most common tumors associated with this syndrome are poorly differentiated lymphomas, such as _Burkitt's lymphoma_ (http://en.wikipedia.org/wiki/Burkitt's_lymphoma) , and leukemias, such as _acute lymphoblastic leukemia_ (http://en.wikipedia.org/wiki/Acute_lymphoblastic_leukemia) (ALL) and _acute myeloid leukemia_ (http://en.wikipedia.org/wiki/Acute_myeloid_leukemia) (AML). Other cancers have also been associated with TLS but are less common. Usually, the precipitating medication regimen includes combination _chemotherapy_ (http://en.wikipedia.org/wiki/Chemotherapy) , but those patients with lymphoma and ALL can be affected with _steroid_ (http://en.wikipedia.org/wiki/Steroid) treatment alone. [_edit_ (http://en.wikipedia.org/w/index.php?title=Tumor_lysis_syndrome&action=edit§ion=2) ] Symptoms and pathogenesis _Hyperkalemia_ (http://en.wikipedia.org/wiki/Hyperkalemia) . _Potassium_ (http://en.wikipedia.org/wiki/Potassium) is mainly an _intracellular_ (http://en.wikipedia.org/wiki/Intracellular) _ion_ (http://en.wikipedia.org/wiki/Ion) . High turnover of tumor cells leads to spill of potassium into the blood. Symptoms usually do not manifest until levels are high (> 7mmol/dL) [normal 3.5-5.0 mmol/dL] and they include * _cardiac_ (http://en.wikipedia.org/wiki/Heart) conduction abnormalities (can be fatal) * severe muscle weakness or paralysis **************Psssst...Have you heard the news? There's a new fashion blog, plus the latest fall trends and hair styles at StyleList.com. (http://www.stylelist.com/trends?ncid=aolsty00050000000014) --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [EMAIL PROTECTED] For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---
