I see from a previous posting that you were 36/1000 in Nov 2004, and then you went to 3.4/1000, and now are back to 25/1000. Most Oncs will give the PCR results as a percentage, and I can't be sure about converting your result to a percentage, but your current result is probably 2.5% -- ask your Onc about that. Whatever the answer, you have increased approx 1 log from your best PCR result, and your past two PCRs have increased. Many Oncs would look at that as worthy of investigating. I would talk to the Onc about: 1) having a Kinase Domain Mutation test done to check for drug resistance (see link below for one lab's explanation of the test) http://www.aruplab.com/TestDirectory/resources_testDirectory/TechnicalBulletins/BCR-ABL1%20Kinase%20Domain%20Mutation%20Jan%202007.pdf 2) depending on what the drug resistance test shows, possibly increasing dosage or switching to another drug --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com -------------------------------------------------
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