I have been a Sprycel user for about 3 months and have had no problems with 
 running nose or cough.  I sense that I have more numbness in my toes and  
feet...but I had that before starting Sprycel.  Good luck to you ...hope  
things clear up!  
 
I have borrowed a format that I have seen on the net from other CMLers that 
 tells in short hand their diagnosis and treatment.  I found it helpful in  
finding others whose treatment was similar to mine.  I have included mine  
below.  Regards, Tom in KY
Tom Dunham, BD:8/1941
DX CML 12-23-2008
MDA Protocol:  Tasigna-400mg; 2xday-1/09
Q PCR bone@ 0.17 7/09
Acute  Pancreatitis-7/5/09
Stopped Tasigna-7/13/09
Q PCRU blood-7-29-09  !
Started Gleevec-400mg/day-7/31/09
Developed rash ~ 8/19/09
Rash  treated with Steriods..improvement
Rash worsens~9/22/09
Stopped  Gleevec-9/28/09
Restarted Gleevec @300mg/day-10/8/09
Stopped  Gleevec-10/13/09-toxic rash\
Q PCR bone-0.05
Started Sprycel @  100mg/day-10/20/09
 
In a message dated 12/10/2009 7:33:39 A.M. Eastern Standard Time,  
[email protected] writes:

One of  the side effects listed on Sprycel is URI. My dr, has me use
Claritan to  help in the winter months with post nasal drip and
congestion. I think it's  related to the Sprycel but have been on
Sprycel for years. It usually  starts late November and goes on through
the Spring. Then, usually clears  for summer months. Never a clear cut
answer but this does help.

On  Dec 9, 10:19 am, kellyelise <[email protected]> wrote:
> Hi  everyone!
>
> I have an appointment this Friday, so I guess I will  find out where I
> stand as far as my numbers go with the  Sprycel.
>
> My question is:  Does anyone else on Sprycel  suffer from runny nose
> and nonstop coughing about an hour or so after  taking the Sprycel?
>
> I had gotten into the habit of taking my  med at night so I could sleep
> through the worst of the side effects of  the Gleevec. Now, on the
> Sprycel, my nose runs and I cough incessantly  to the point I have to
> sit upright and can't sleep. Cough drops help.  My GP put me on a
> steroid nasal spray - it helped some, but not  enough.
>
> It took me MONTHS to figure out what was causing these  coughing spells
> at night. I thought it was allergies, dust, cat  dander, etc. Finally,
> HELLO, I made the connection between when I take  my med and the
> subsequent coughing. I always take it with food, so,  that's not an
> issue. I found drinking tea helps a little and drinking  lots of water
> helps some. It got especially worse after I had that  stinkin' flu. No
> coughing fits during the day, although I am taking  the med at around 3
> p.m. so the coughing stops before I go to  bed.
>
> I went to an ENT one time due to coughing and sneezing  constantly. She
> told me it was from reflux irritating the esophagus  which was causing
> my sinuses to run to coat the esophagus and protect  it from the
> reflux. Made a lot of sense and the anti-reflux pill she  put me on
> greatly reduced the symptoms. Wondering if that's what is  going on
> here.....and can't take anti-reflux meds with  Sprycel.
>
> Opinions always greatly appreciated!
>  Kelly

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