Hi Zavie,
My PCR results were as follows:

BCR-ABL p210 transcripts were detected with a p210 to ABL RATIO OF  0.24626
My doctor was really happy with this.
I have been on Sprycel for about 7 months now.  As you know, I had  
relapsed on Gleevec and then on Tasigna.
I think the Sprycel is going to put me in remission.
Blessings
Jeanie<3
 
 
In a message dated 1/24/2010 8:38:02 A.M. Pacific Standard Time,  
[email protected] writes:

Zavie...I am still confused about the log reduction scale vrs the  absolute 
pcr rating.  If you are at a pcr of 0.05 isn't that good  regardless of 
what the log reduction was?  Thanks for all your great work  in keeping us in 
the loop!  Regards, Tom in KY
 
 
In a message dated 1/23/2010 11:16:28 P.M. Eastern Standard Time,  
[email protected] writes:

Hi Daniel,
 
Whose idea was it to try and get to PCRU? All the literature says that  
once you reach a 3 log reduction your chances of relapsing with your CML are  
the same as if you reached PCRU.
 
Zavie


On Tue, Jan 19, 2010 at 4:15 PM, daniel <[email protected]_ 
(mailto:[email protected]) >  wrote:

hi all,
i recently switched to nilotinib (tasigna),  in an effort to get my pcr
down to zero (had decent response on  gleevec, but wanted something
more aggressive to try to get down to  zero). anyway, i started
nilotinib about 7 days ago and have developed  a rash oAll the literature 
says that once you n my face that
looks like  a moderate sunburn, as well as a really intense itch on my
scalp.  anyone have any tips for managing these side effects? they  are
not intolerable, but are quite annoying! any advice would be  much
appreciated.

thanks,
daniel

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-- 
Zavie Miller (age 71)
67 Shoreham Avenue
Ottawa,  Canada, K2G 3X3
dxd AUG/99
INF OCT/99 to FEB/00, CHF
No meds FEB/00  to JAN/01
Gleevec since MAR/27/01 (400 mg)
CCR SEP/01. #102 in Zero  Club
2.8 log reduction Sep/05
3.0 log reduction Jan/06
2.9 log  reduction Feb/07
3.6 log reduction Apr/08
3.6 log reduction  Sep/08
3.7 log reduction Jan/09
3.8 log reduction May/09
3.8 log  reduction Aug/09
e-mail: [email protected]_ (mailto:[email protected]) 
Tel:  613-726-1117
Fax: 613-482-4801
Cell: 613-282-0204
Yahoo ID:  zaviem

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