I too was diagnosed in February and began Gleevec at 400....I tried to stay on Gleevec but experienced such severe side effects at the therapeutic dose that I was placed on Tasigna....I got my heart checked every two weeks the first few months...and whenever there has been a doseage change...Tasigna has been much better that Gleevec, no swelling, IBS, etc..I have far more energy....the skin rashes do get better with time and there are things you can take for them, constipation for me but mes help that........if your sugars go up...you can take meds for the diabetes..I became a diabetic on the Tasigna..was not before...but try not to let that scare you..learning to control sugars with medication taken with the Tasigna and throughout the day...has not been bad...I want to stay on Tasi truly, but for me, it's affecting my liver enzymes too much..I am very sensitive..this dose not happen often...so I am on the way to Sprycel..I am scared as well..but as MIllie said, we need to find what works for us the best out of the options....sometimes, the oncologists will decide to lower the dose to what is tolerable for our systems as long as we are in remission...it' s a balancing act..I wish you well..try not to fear too much..it may surprise you....it may be much easier for you and may not effect yoru heart any different that Gleevec...have your heart checked regularily to ease your anxiety....no one can predict what side efffects you will or will not have because everybody responds differently to these meds...remember, you are not alone...we are here...My best to you, Beth
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