The way it was explained to me is that since CML affects the chromosomes, it is by definition genetic but there is no evidence to support the notion that it is heredic. It is more like normal chromosones becoming fused together creating the mutated "Phillidelphia chromosone" It is more like a "fluke" of nature than an inherited gene and no one knows what causes it or if anything causes it. "Flukes" cannot really be explained. JD in Texas
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