Hi Fran, Gere is a blog post that expresses my dosage dilemma...I have been on Sprycel 100 mg, six days a week for approximately 9 months. I do suffer from some fatigue and overall yuckiness! http://www.leukemiasurvivor.co/2011/04/dasatinib-sprycel-my-dosage-dilemma.html
Hope this is helpful, Michele On Tue, Feb 28, 2012 at 5:26 PM, <[email protected]> wrote: > ** > Beth...my journey is outlined below....Good to hear that you are doing > well on 50 mg. I am going to try to go to that level and see if it helps > with the tiredness. Keep in touch! Tom in KY > Tom Dunham, BD: 8/1941 > DX CML 12-23-2008 > MDA Protocol: Tasigna-400 mg, 2xday-1/09 > On FLecainide for Atrial Fibrillation...episodes > Q PCR bone @ 0.17 on 7/09 > Acute Pancreatitis-7-5-09; Stopped Tasigna > Q PCR Blood; 7-29-09 Undetectable > Started Gleevec-400 mg/day--7-31-09 > Developed rash-8-19-09..worsens 9-22-09 > Stopped Gleevec-9-28-09 > Restarted Gleevec 300 mg/day 10-8-09 > Stopped Gleevec..toxic rash..10-13-09 > Q PCR Bone: 0.05 > Started Sprycel @ 100 mg/day-10-20-09 > Some AF, Increased Flecainide (1&1/2 per day) > Q PCR Bone; 0.07 (ZM's Club #1292) 2-4-10 > Stopped Alcohol/Caffeine ..AF stopped > Q PCR Blood 0.01-- 7-27-10 > Q PCR Bone 0.01...1-25-11 > Q PCR Blood-Undetectible: 5-19-11 > Pleural Effusion, CE, 12-7-11..Stopped Sprycel > Prednisone 50 mg/day..gradual reduction > Pleural Effusion clear 12-21 11 > Started Sprycel 70mg/day 12-23-11 > > In a message dated 2/28/2012 5:16:15 P.M. Eastern Standard Time, > [email protected] writes: > > Yes, 50 daily is a half dose, which I have been on successfully for my > blood labs for 15 months. I am going down to 40 a day next Month to see > if it helps with some elevated CPK or muscle enzymes that cause a lot > of fatigue for me. I know many people on 50 sprycel in complete > remission. Just as a word of reassurance regarding potential side > effects, I had very bad headaches in the beginning which do go away in > a few weeks, but needed to pre- medicate for them to keep them from > getting too bad. If your son has a hx of swelling, then they may put > him on a diuretic to ensure that he doesn't have this issue. I wish him > and you lots of good luck and well wishes. May he find a low dose of > sprycel very effectivie and not need to ever go up on his dose. Warm > regards, Beth in Chicago. > > > -----Original Message----- > From: Tom Dunham <[email protected]> > To: cmlhope <[email protected]> > Cc: cmlhope <[email protected]> > Sent: Tue, Feb 28, 2012 12:57 pm > Subject: Re: [CMLHope] Young and Strong > > > Hi...have been on 100 mg Sprycel for 18 months. Developed pleural > effusion...now on 70 mg....will keep u posted. Hang in there! Tom in > KY > > > T.E.D.---Sent from my iPad > > > On Feb 27, 2012, at 11:51 PM, Joyce Mesnarich <[email protected]> wrote: > > > > > My husband (72) was put on Sprycel about 2 years ago---50 mg, the > lowest dose according to Dr. Talpaz, a great CML specialist. It has > worked well for him and he has less side effects than when he was on > Gleevec, which he could not take, as it turns out. Hope your son does > well on Sprycel. We think it is a great drug. > Joyce in IL > > On Feb 27, 2012, at 9:21 AM, David Stroud wrote: > > > Hi Group > I have kept up with this group now for almost 9 yrs. My son Jonathan > was dx in 2003 at the age of 9. Many I know will remember him. > Zavie was a great encourager for us. I know he is missed. > > Jonathan recently has had difficulties with his counts bouncing > around.. 84/100k 47/100k 28/100k > Use to continue at 3-5/100k > He is now loosing weight also but was never a big guy.. 5'9 at 109lbs. > Alittle concerned. Doc thinking of taking him off the gleevec of 400mg > daily to the new Sprycel. I want to statr at a low dosage if so. > > Depression has set in also. But alot has to do with teenage life. > For those that have switched to Sprycel.. what is the "low Dosage" > isn't it 50 daily? > > Each One Take care > Fran > Mom > > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google > Groups "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope > > > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google > Groups "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google > Groups "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope > > > > > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope -- [email protected] www.LearntoBallroomDanceOnline.com -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope
