Hi all -
Gleevec was approved by the FDA in the US for adults with
dermatofibrosarcoma in 2006. As best I can tell the request coming in to
this group, and to other patient groups, is from someone in a country where
it is more difficult to get Gleevec and who may be using a translation tool
to communicate in English. 

Here is some information from Walgreens: It is thought that Gleevec can help
treat dermatofibrosarcoma protuberans (DFSP) by blocking the signals from an
abnormal protein made by a gene called the PDGFR fusion gene. DFSP are
tumors that grow under the top skin layer, and it seems that the PDGFR
fusion gene makes the abnormal protein that causes cancerous cells to grow.
Gleevec may work by blocking the messages from that abnormal protein that
could harm the normal function of cells.

It is an individual choice, of course, on whether to help someone out by
sending drugs to them, but one should be aware of the risks taken when doing
so and be fully informed.

Regards,
Pat

-----Original Message-----
From: [email protected] [mailto:[email protected]] On Behalf
Of Suzieq
Sent: Saturday, March 17, 2012 7:53 AM
To: CMLHope
Subject: [CMLHope] Re: need Cleevec for my son

Michelle:

I'm with you on this......it was the first thing I thought of when I saw the
post.  2nd, was the "dermatofibrosarcoma" ??
My antenna's came up,  sorry.  And, as you pointed out,  the spelling or
poor grammar.  I liked Pat's response.

Suzieq

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