Love it, Captain Dave! Marcie
Sent from my iPhone > On Nov 15, 2014, at 7:20 AM, Myvety2k via CMLHope <cmlhope@googlegroups.com> > wrote: > > Well thank you Marcie, I have this idea, let's make Skip a Fleet Admiral, > I'm not sure but I think he as had CML the longest. Will make Marty Admiral > that's next in line and I'll be Captain Dave. When I first started flying > real planes my instructor used to call me Capt. Dave. So when I started > flying RC airplanes last year I crashed a lot so one of the guy's would call > me Danger Dave. Of course now I can fly as good as the rest of the guys. > But their used to be a lot of broken plane parts on the field. > > greenie > > > In a message dated 11/14/2014 10:51:23 P.M. Eastern Standard Time, > cmlhope@googlegroups.com writes: > Greenie, we are all so thrilled you are doing well. If Marty is our captain, > I think you must be his first officer! > > Marcie > > Sent from my iPad > >> On Nov 14, 2014, at 9:38 PM, Myvety2k via CMLHope <cmlhope@googlegroups.com> >> wrote: >> >> I would like to thank each and everyone of you for your warm hearted replies. >> >> greenie >> >> In a message dated 11/14/2014 9:36:20 P.M. Eastern Standard Time, >> cmlhope@googlegroups.com writes: >> Thank you Marty, I should have added that I went into remission within 6 >> months after starting Gleevec. I was having to get blood work every 3 >> months now I get blood work every 6 months. I've had 27 BMB's so I'm glad >> they do it by testing your blood. We all have our good days and then their >> are a few bad days to so like my late Aunt used to say just take one day at >> a time. And that's what I do. Today was one of those bad days but tomorrow >> I'm sure will be better it always is. Everyone please take care of >> yourself's I'm so lucky my wife Grace who takes good care of me. >> >> greenie >> >> >> In a message dated 11/14/2014 7:35:36 P.M. Eastern Standard Time, >> wa2...@gmail.com writes: >> Greenie, >> >> Hey, what took you so long? I am thrilled to hear this wonderful news. You >> are blessed. >> >> 18's, >> >> Marty >> >>> On Fri, Nov 14, 2014 at 2:29 PM, icandoallttc via CMLHope >>> <cmlhope@googlegroups.com> wrote: >>> Yahoo Greenie >>> So happy for you!! >>> Blessing >>> Jeanie >>> >>> Sent from my iPhone >>> >>>> On Nov 11, 2014, at 4:05 PM, Myvety2k via CMLHope >>>> <cmlhope@googlegroups.com> wrote: >>>> >>>> I received my results back from my 6 month blood work today and I'm >>>> Negative on BCR-ABL. >>>> >>>> greenie >>>> >>>> In a message dated 11/11/2014 2:14:49 P.M. Eastern Standard Time, >>>> cmlhope@googlegroups.com writes: >>>> Happy Veterans Day to all >>>> JeanieđČđșđžđșđž >>>> >>>> Sent from my iPhone >>>> >>>>> On Nov 11, 2014, at 1:56 PM, Myvety2k via CMLHope >>>>> <cmlhope@googlegroups.com> wrote: >>>>> >>>>> Thank you Elizabeth, I served 6 years in the Navy. >>>>> >>>>> greenie >>>>> >>>>> In a message dated 11/11/2014 1:43:34 P.M. Eastern Standard Time, >>>>> ksnwo...@prodigy.net writes: >>>>> Thinking of you all. Nick is critically anemic due to Gleevec. Hope >>>>> Richard H., Shannon, Bobbie Doyle, and all keep up your sharing of info. >>>>> thanks so much Marty for the reports from the clinical trials to reduce >>>>> or stop Gleevec. >>>>> Thank you to all Veterans on this day. Elizabeth Woods >>>>> >>>>> >>>>> On Tuesday, November 11, 2014 4:32 AM, "cmlhope@googlegroups.com" >>>>> <cmlhope@googlegroups.com> wrote: >>>>> >>>>> >>>>> cmlhope@googlegroups.com Google Groups >>>>> Topic digest >>>>> View all topics >>>>> Glivec and studies of stopping the drug - 1 Update >>>>> Digest for cmlhope@googlegroups.com - 6 updates in 2 topics - 1 Update >>>>> Glivec and studies of stopping the drug >>>>> Richard H <rbhuffm...@gmail.com>: Nov 10 09:05PM -0800 >>>>> >>>>> Yes. This was the reason I stopped Gleevec. I was also had Iron Deficient >>>>> Anemia. I had to infuse the iron to help try to recover my RBC count >>>>> because was below 9. I was also still taking Gleevec while doing this. >>>>> On Monday, November 10, 2014 12:56:18 AM UTC-6, Shannon L wrote: >>>>> Back to top >>>>> Digest for cmlhope@googlegroups.com - 6 updates in 2 topics >>>>> >>>>> "Sue" <hol...@iinet.net.au>: Nov 10 07:13PM +0800 >>>>> >>>>> Hi Shannon >>>>> >>>>> >>>>> >>>>> There is also the Destiny Trial in the UK which is reduction down to >>>>> 200mg for 12 months and then stop (there has been no report until after >>>>> Dec 2014) >>>>> >>>>> The next Trial is named Spirit3 to see if people are being over medicated >>>>> >>>>> >>>>> >>>>> The Australian Survey will have 600 participants >>>>> >>>>> >>>>> >>>>> Sue Hurt >>>>> >>>>> (Australian) >>>>> >>>>> >>>>> >>>>> From: cmlhope@googlegroups.com [mailto:cmlhope@googlegroups.com] >>>>> Sent: Monday, 10 November 2014 6:22 PM >>>>> To: Digest recipients >>>>> Subject: [CMLHope] Digest for cmlhope@googlegroups.com - 6 updates in 2 >>>>> topics >>>>> >>>>> >>>>> >>>>> >>>>> cmlhope@googlegroups.com >>>>> >>>>> <https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#!overview> >>>>> Google Groups >>>>> >>>>> <https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#!overview> >>>>> >>>>> >>>>> Topic digest >>>>> View all topics >>>>> >>>>> * Glivec and studies of stopping the drug - 5 >>>>> Updates >>>>> >>>>> * Glivec and studies of stopping the drug - 1 Update >>>>> >>>>> <http://groups.google.com/group/cmlhope/t/839da881a2e6e455?utm_source=digest&utm_medium=email> >>>>> Glivec and studies of stopping the drug >>>>> >>>>> >>>>> Shannon L <shannonl.cam...@gmail.com <mailto:shannonl.cam...@gmail.com> >>>>> >: Nov 09 03:58AM -0800 >>>>> >>>>> Hi All My name is Shannon I live in Sydney Australia >>>>> Its been awhile since I have posted. >>>>> I was diagnosed 1998 and after a few years went onto sti571 (glivec) and >>>>> achieved remission within 2 months and I have been it ever since about 14 >>>>> yrs. >>>>> They are inviting participants (in Australia) to take a survey of >>>>> stopping >>>>> glivec I image they will do a study of stopping the drug. >>>>> My question is does everyone know of the study done in USA of the stats >>>>> of >>>>> stopping they have indicated in this survey info that the percentage of >>>>> success is 30-40% to me that SEEMS LOW what do you think. >>>>> I do have some problems but I am stable on glivec. >>>>> I hope this emil finds everyone well >>>>> Shannon >>>>> >>>>> >>>>> Marty Gartenberg <wa2...@gmail.com >>>>> <mailto:wa2...@gmail.com> >: Nov 09 07:46AM -0500 >>>>> >>>>> Hi Shannon, there is a study called the STIM that is going on in the UK >>>>> and >>>>> it talks about Imatinib being stopped. It is kind >>>>> of lengthily however it >>>>> does go into detail. >>>>> Good luck to you, and I have always said there will be a cure for CML in >>>>> our lifetimes. >>>>> If you follow any of my posts I always end them with two numbers. They are >>>>> 18 which is the symbol for life. >>>>> 18's to you Shannon >>>>> Marty >>>>> PS Shannon I encourage you to post any time that you like. There will >>>>> usually be someone that may be able to answer your questions. Besides that >>>>> we are all here to learn from and help each other >>>>> Can Imatinib Be Stopped? >>>>> >>>>> Goodwin, Peter >>>>> Article Outline >>>>> [image: Collapse Box]Author Information >>>>> >>>>> ASH Abstracts 186 and 187 >>>>> >>>>> SAN FRANCISCOâThe early promise of the tyrosine kinase inhibitor (TKI) >>>>> imatinib for treating chronic myeloid leukemia (CML) has continued to be >>>>> fulfilled following the release of seven-year follow-up data at the ASH >>>>> Annual Meeting here from the International Randomized Study of Interferon >>>>> versus STI 571 (imatinib) (IRIS) with 553 patients. >>>>> >>>>> With diminishing rates of progression each year beyond year >>>>> three, the case >>>>> for stopping imatinib altogether was also discussed at the meeting >>>>> following release of results from two studies in which the drug was >>>>> discontinued among patients who had achieved enduring complete molecular >>>>> responses to it for more than two years. >>>>> >>>>> IRIS investigator Stephen G. O'Brien MD, PhD, Senior Lecturer in >>>>> Experimental Hematology at Northern Institute for Cancer Research of >>>>> University of Newcastle upon Tyne, UK, gave the latest IRIS results to a >>>>> packed audience at the meeting, showing an event-free survival rate of >>>>> 81%, >>>>> freedom from progression to accelerated phase/blast crisis of 93%, and an >>>>> estimated overall survival rate of 86%, from the standard dose of 400 mg >>>>> imatinib daily. >>>>> >>>>> And in the presentation that followed, François-Xavier Mahon, MD, >>>>> Professor >>>>> at Victor SĂ©galen University in Bordeaux, France, released early data from >>>>> the Stop Imatinib (STIM) study, noting that remissions continued in about >>>>> half of the patients after investigational discontinuation of imatinib >>>>> therapyâwith a non-significant trend showing that patients previously >>>>> treated with interferon were more likely to be among those whose >>>>> remissions >>>>> persisted without drugs. >>>>> >>>>> Dr. O'Brien said that in IRIS the projected cytogenetic response rate to >>>>> imatinib (by Kaplan Meyer analysis) was 82%, and that after seven years of >>>>> follow-up 60% of patients were still on imatinib, with 57% of all patients >>>>> still in complete cytogenetic response (CCR). >>>>> >>>>> The impression that CCR holds the key to a âcureâ of CML was strengthened >>>>> by comments he made after his talk: >>>>> >>>>> âIt seems that if you maintain your CCR for, say, three years, the chance >>>>> of regressing at that point is essentially zero. So, achieving a CCR is, I >>>>> guess, what we call a âsafe havenâ for the majority of patients: If you've >>>>> achieved that and sustained it for, say, three years, you're in pretty >>>>> good >>>>> shape and the chance of progressing is virtually nil,â he said. >>>>> Back to Top >>>>> <http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx# >>>>> >>>>> <http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx> >>>>> > >>>>> | Article Outline >>>>> Diminishing Rates of Relapse >>>>> >>>>> These words reflect the diminishing rates of relapse observed in the IRIS >>>>> study in successive years. Rates of progression to accelerate phase or >>>>> blast crisis each year were low at all timesâwith rates rising in the >>>>> first >>>>> two years (1.5% in the first year; 2.8% in the second year) and >>>>> then >>>>> diminishing after that (1.6%, 0.9%, 0.5%, 0%, 0.4% in years 3, 4, 5, 6, >>>>> and >>>>> 7, respectively)âwith only a single patient having disease progression to >>>>> accelerate phase or blast crisis between years six and seven. >>>>> [image: Figure. FRANOIS-XAVI...] >>>>> Figure. FRANOIS-XAVI... >>>>> Image Tools >>>>> >>>>> The total annual event rates, including loss of molecular complete >>>>> remission and death, were similarly low (3.3% and 7.5%) in years one and >>>>> two, and diminished thereafter (4.8%, 1.7%, 0.8%, 0.3%, and 2.0% in years >>>>> three through seven). >>>>> >>>>> These data only apply, of course, to the majority of patients who prove >>>>> sensitive to imatinib, and Dr. O'Brien noted that many patients who are >>>>> resistant or refractory to the TKI are now candidates for other drugs and >>>>> in some cases, allogeneic transplantation. >>>>> >>>>> Dr. O'Brien summed up his feelings about the current state of the art >>>>> concerning imatinib therapy for CML: âI think it's encouraging on two >>>>> fronts. One is that there's nothing new in years >>>>> six and seven to cause >>>>> alarm in terms of safety events. And the second isâparticularly in >>>>> patients >>>>> who achieved a complete cytogenetic responseâI think we can be very >>>>> reassured that the vast majorityâespecially if you have that CCR for three >>>>> yearsâare doing extremely well, with very few of those progressing.â >>>>> Back to Top >>>>> <http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx# >>>>> >>>>> <http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx> >>>>> > >>>>> | Article Outline >>>>> STIM Study >>>>> >>>>> Encouraging data on long-term remission of CML among patients treated with >>>>> imatinib gave rise to the French initiative to conduct a pilot study with >>>>> 15 patients looking at stopping imatinib, and following this the >>>>> multicenter STIM study with 50 patients, which began in July 2007 but >>>>> which >>>>> has already yielded earlyâbut provocativeâevidence that remission from CML >>>>> can continue even after imatinib is stopped. >>>>> >>>>> Dr. Mahon said that patients were recruited into >>>>> these studies only if they >>>>> had received imatinib for at least three years and achieved sustained >>>>> complete molecular remission (CMR) for two years before experimentally >>>>> stopping the drug. >>>>> >>>>> The definition of sustained CMR was strict: BCR-ABL/ABL had to be below a >>>>> detection threshold corresponding to a 5-log reduction (undetectable >>>>> signal >>>>> using RQ-PCR) for at least two years. Molecular relapse was defined as >>>>> RQ-PCR positivity detected in two successive assays, and patients who >>>>> relapsed were then retreated with imatinib (successfully) at a dose of 400 >>>>> mg daily. >>>>> >>>>> In the latest follow-up of the pilot study, Dr. Mahon said that seven out >>>>> of 15 patients had relapse within six months and all were restored to CMR >>>>> by re-treatment with imatinib. The remaining eight patients were still in >>>>> CMR a median of 37 months after stopping the drug. >>>>> >>>>> All of the patients in the pilot study had been treated with interferon >>>>> before receiving imatinib, most of them responding to it. This raised the >>>>> suggestionâwhich Dr. Mahon discussed in his talk at the ASH meetingâthat >>>>> interferon may have conferred a benefit among patients who were >>>>> subsequently treated with imatinib. >>>>> >>>>> Half of the patients in the STIM study had been pretreated with >>>>> interferon, >>>>> and some provocativeâbut as yet not statistically significantâdata have >>>>> emerged showing an advantage among those who had >>>>> previously received >>>>> interferon before going on to imatinib therapy. >>>>> >>>>> By July 2008, 10 of the 15 patients who were still in CMR had received >>>>> prior interferon. The latest assessment from a slide Dr. Mahon >>>>> presented >>>>> showed that 27 out of 49 patients followed for more than six months had >>>>> had >>>>> disease relapse; 14 of these had received only imatinib and the remaining >>>>> 13 had been previously treated with interferon, while only two of the >>>>> seven >>>>> patients in STIM who have so far continued in CMR for 14 months had been >>>>> treated with imatinib alone. >>>>> >>>>> Dr. Mahon summed up his interim conclusions by stating that they have >>>>> confirmed that CMR can be sustained after stopping imatinib, and that >>>>> although there seems to be an [as yet statistically unconfirmed] advantage >>>>> among the patients who received interferon, it is possible to stop the >>>>> drug >>>>> in patients with sustained CMR even among those treated with imatinib >>>>> alone. >>>>> >>>>> He reported that the probability of survival without molecular relapse >>>>> nine >>>>> months after discontinuing imatinib was 46%, with the curve looking flat, >>>>> so far, out to 15 months. Importantly, the STIM study found that all >>>>> patients were sensitive after imatinib re-challenge. >>>>> Back to Top >>>>> <http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx# >>>>> >>>>> <http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx> >>>>> > >>>>> | Article Outline >>>>> âRecurring Questionâ >>>>> >>>>> When Dr. O'Brien was asked for a comment on Dr. Mahon's conclusion from >>>>> the >>>>> initial pilot study and the early results from the STIM study, he said, >>>>> âI'm fascinated by it. There's probably a bit of a cultural difference, I >>>>> think, because most of my patients in the UKâwhen I suggest >>>>> [stopping]âdon't want to hand their pills back, and want to carry on. >>>>> [image: Figure. STEPHEN G. O...] >>>>> Figure. STEPHEN G. O... >>>>> Image Tools >>>>> >>>>> âI think that's driven by the fact that they are tolerating the drug well. >>>>> There are no safety concerns emerging with the long-term follow-up. And >>>>> it's obviously having good efficacy in them. But this is a recurring >>>>> question that I think we'll see more and more ofâand the French study is >>>>> very important.â >>>>> Back to Top >>>>> <http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx# >>>>> >>>>> <http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx> >>>>> > >>>>> | Article Outline >>>>> Low Toxicities >>>>> >>>>> In the UK, he noted, the preference for continuing imatinib could be >>>>> explained by relatively low toxicities, which were not a significant >>>>> barrier to its use, with neutropenia and thrombocytopenia being minor >>>>> toxicities that are merely irritating over time. >>>>> >>>>> âGI toxicity like diarrhea, for example, and a feeling of fatigue and >>>>> malaise, sometimes, and muscle cramps can be troublesome in some patients >>>>> over the years. But they're usually minor toxicities which, after many >>>>> years, become rather wearing, rather than major toxicities,â he said. >>>>> >>>>> The bottom line for clinicians treating their patients with CML, according >>>>> to Dr. O'Brien's interpretation of his IRIS results, is that imatinib at >>>>> 400 mg remains the current standard for first-line drug therapy, even >>>>> though there are exciting data among patient cohorts treated with >>>>> nilotinib >>>>> and dasatinib first-line, with cytogenetic response rates in excess of >>>>> 95%. >>>>> >>>>> âI thinkâfor the futureâwhere we're going is to do comparative Phase III >>>>> studies with the tyrosine kinase inhibitors in newly diagnosed patients to >>>>> see if we can improve on imatinib. Because although the imatinib data is >>>>> reassuring, it's clear that at six or seven years, perhaps a third of >>>>> patients are not continuing on imatinib,â he said. >>>>> >>>>> *Supported by funding from Genentech BioOncology and Biogen Idec.* >>>>> >>>>> © 2009 Lippincott Williams & Wilkins, Inc. >>>>> >>>>> >>>>> >>>>> Shannon L <shannonl.cam...@gmail.com <mailto:shannonl.cam...@gmail.com> >>>>> >: Nov 09 03:52PM -0800 >>>>> >>>>> Hi Everyone >>>>> Thankyou Marty for the research information it was very informative, so >>>>> they are combining stopping with interferon unfortunately I can't >>>>> tolerate >>>>> it I remember the first time before glivec. >>>>> I hope everyone is having a wonderful day. >>>>> >>>>> On Sunday, November 9, 2014 10:58:55 PM UTC+11, Shannon L wrote: >>>>> >>>>> >>>>> Richard H <rbhuffm...@gmail.com <mailto:rbhuffm...@gmail.com> >: Nov 09 >>>>> 09:33PM -0800 >>>>> >>>>> What a great record. You didn't indicate how much Gleevec you are taking. >>>>> I have read that several CMLers are taking reduced amounts and reaming in >>>>> remission. I have seen a post by a lady that said see was very petite and >>>>> she was only taking 100mg instead of 400mg. >>>>> I don't know the percentage or of a combined results From the different >>>>> studies I read sometime ago I believe the range you have is consistent >>>>> with >>>>> what I have read. You can read my results below. My ONC told be I needed >>>>> to end my almost 6 year vacation and I am trying to >>>>> requalify for a lower >>>>> copay for Bosutinib. I have tested and they found no mutation. I have >>>>> studied the side effects and I will be meeting with a Nurse to go over >>>>> the >>>>> side effects. Due to my other problems I am concerned about all the >>>>> interactions with those Meds. >>>>> I hope this has helped you. >>>>> >>>>> Richard H. >>>>> >>>>> Dxd 2/2003 >>>>> >>>>> 400mg Gleevec 3/2003 >>>>> >>>>> Undetectable 11/03 >>>>> >>>>> RT-PCR negative 11/04 >>>>> >>>>> QT-PCR .003 11/05 >>>>> >>>>> RBC 8. >>>>> >>>>> Gleevec Vacation 11/06-6/07 >>>>> >>>>> Iron infusion 11/06 >>>>> >>>>> Transfusions 12/06-5/07 >>>>> >>>>> QT-PCR .007 >>>>> >>>>> Gleevec 1/08 -5/08 >>>>> >>>>> Procrit 8/08-11/08 >>>>> >>>>> Gleevec Vacation 7/08-Present >>>>> >>>>> QT-PCR .003 4/09 >>>>> >>>>> QT-PCR .0015 6/09 >>>>> >>>>> QT-PCR .0021 9/09 >>>>> >>>>> QT-PCR .0028 1/10 >>>>> >>>>> QT-PCR .001 4/10 >>>>> >>>>> QT-PCR .00468 10/10 >>>>> >>>>> QT-PCR 1.049% 2/11 >>>>> >>>>> QT-PCR .0612% 8/11 >>>>> >>>>> QT-PCR 2.616 % 2/12 >>>>> >>>>> QT-PCR 2.410% 8/12 >>>>> >>>>> RT-PCR 9.183% 4/13 >>>>> >>>>> RT-PCR 4.57% 6/13 >>>>> >>>>> RT-PCR 10.183% 10/13 >>>>> >>>>> RT-PCR 10.577% 2/14 >>>>> >>>>> RT-PCR 16.050% 5/14 >>>>> >>>>> On Sunday, November 9, 2014 5:58:55 AM UTC-6, Shannon L wrote: >>>>> >>>>> >>>>> >>>>> Shannon L <shannonl.cam...@gmail.com <mailto:shannonl.cam...@gmail.com> >>>>> >: Nov 09 10:56PM -0800 >>>>> >>>>> Hi Richard H >>>>> >>>>> Yes Glivec 400 mg has been good to me I have been very stable on the >>>>> drug, >>>>> Wow 6 years off glivec thank you so much for sharing your results just a >>>>> question in your first holiday off glivec you had an >>>>> iron injection is this >>>>> because of cml? I am contemplating a small break as my stomach problems >>>>> seem to be increasing and are at times very debilitating. I know I have >>>>> been on many meds prior to glivec (chemo twice, cytarabine, hydroxia, and >>>>> interferon) and Im sure my body sometimes struggles with it all. >>>>> >>>>> On Sunday, November 9, 2014 10:58:55 PM UTC+11, Shannon L wrote: >>>>> >>>>> Back to top >>>>> >>>>> <http://groups.google.com/group/cmlhope/t/22ca310a00448c54?utm_source=digest&utm_medium=email> >>>>> Glivec and studies of stopping the drug >>>>> >>>>> >>>>> myvet...@aol.com <mailto:myvet...@aol.com> : Nov 09 07:32AM -0500 >>>>> Back to top >>>>> You received this digest because you're subscribed to updates for this >>>>> group. You can change your settings on the group membership page. >>>>> To unsubscribe from this group and stop receiving emails from it send an >>>>> email to cmlhope+unsubscr...@googlegroups.com. >>>>> >>>>> >>>>> -- >>>>> -- >>>>> [CMLHope] >>>>> A support group of http://cmlhope.com >>>>> ------------------------------------------------- >>>>> >>>>> You received this message because you are subscribed to the Google Groups >>>>> "CMLHope" group. >>>>> To post to this group, send email to CMLHope@googlegroups.com >>>>> To unsubscribe from this group, send email to >>>>> cmlhope-unsubscr...@googlegroups.com >>>>> For more options, visit this group at >>>>> http://groups.google.com/group/CMLHope >>>>> --- >>>>> You received this message because you are subscribed to the Google Groups >>>>> "CMLHope" group. >>>>> To unsubscribe from this group and stop receiving emails from it, send an >>>>> email to cmlhope+unsubscr...@googlegroups.com. >>>>> For more options, visit 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To post to this group, send email to CMLHope@googlegroups.com To unsubscribe from this group, send email to cmlhope-unsubscr...@googlegroups.com For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to cmlhope+unsubscr...@googlegroups.com. For more options, visit https://groups.google.com/d/optout.
