Blending engineering and medicine: novel analyses of electrocardiogram for
prediction and prevention of sudden cardiac death is coming at 10/28/2019 -
4:00pm

Gilfillan Auditorium
Mon, 10/28/2019 - 4:00pm

Larisa Tereshchenko
Associate professor of medicine , Knight Cardiovascular Institute

Abstract:
Heart disease is the #1 killer in the United States. Sudden cardiac death is
a major contributor to cardiovascular mortality and a tragic event for a
community and family members. Understanding mechanisms of cardiac arrhythmias
is a key factor for further reduction of cardiovascular disease burden and
mortality. For initiation of arrhythmia, two components are necessary:
trigger and the susceptible electrophysiological substrate. Advances in
computer science, digital signal processing, and understanding of cardiac
arrhythmia mechanisms led to the development of novel mechanistic
electrocardiographic and vectorcardiographic measures. We use a widely
available, inexpensive, and non-invasive tool (resting 12-lead ECG) to
characterize the electrophysiological substrate of cardiac arrhythmias and
sudden cardiac death. Then, we study associations of electrocardiographic
phenotype with genomics to understand underlying biology of the
electrophysiological substrate. In my talk I will present my translational
program, my effort of building Big Data resource (ECGome consortium) and
outline opportunities for our collaboration/opportunities for students.

Bio:

Read more:
http://eecs.oregonstate.edu/colloquium/blending-engineering-and-medicine... 
[1]


[1] 
http://eecs.oregonstate.edu/colloquium/blending-engineering-and-medicine-novel-analyses-electrocardiogram-prediction-and
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