Additionally, since this was asked before, I am running COOT 0.5.2

Ed

On Tue, Jun 2, 2009 at 6:00 PM, Edward Miller <[email protected]> wrote:

> Hey Paul,
>
> I believe I have figured out the problem - but not the solution.
>
> On closer inspection, it wasn't just  the numerically labelled chain IDs
> that weren't read, a few of the alphabetical chains were also not read.
>
> What happens is REFMAC restarts atom numbering once 100000 atoms are
> reached when outputting the refined coordinates.
>
> COOT was reading in the first 99999 atoms, numbered 1-99999 by REFMAC, then
> the second 99999 atoms, again numbered 1-99999 by REFMAC. At this point,
> however, REFMAC for some reason made the next atom 100000 and then restarted
> numbering at 1. This atom, numbered 100000, was not read by COOT and nor
> where any subsequent atoms.
>
> The input coordinates that I used for REFMAC, which again consisted of 60
> chains, was created by combining sets of 10mers, thus the atom numbering
> restarted after each 10 chains. REFMAC had no problem refining these
> coordinates and COOT had no problem reading these coordinates.
>
> To further confirm that COOT is failing once it reads atom 100000, I wrote
> a little perl script to properly renumber the atoms in the REFMAC refined
> coordinates. In this file, there are correctly 246960 atoms.
>
> Within my perl script, I formatted the output such that the atom numbers
> eat into the spaces after "ATOM"  like so:
>
> ATOM 246960  O   LEU 7 736      64.294  96.393-111.576  1.00 34.97
>
>
> I see now that the last atom COOT reads in is atom number 99999.
>
>
> Perhaps, I fear, this is a problem with the PDB format - that the column
> width for atom numbers can not accommodate more than 99999 atoms.
>
> Ed
>
> On Tue, Jun 2, 2009 at 9:39 AM, Paul Emsley <[email protected]>wrote:
>
>> Edward Miller wrote:
>>
>>> Hey Folks,
>>>
>>> I'm working on refining a full capsid containing 60 chains.
>>>
>>> Using the chain ID column, I've numbered my chains A-Z, a-z, and 0-7. I
>>> was successfully able to refine my capsid in refmac using this chain ID
>>> naming scheme.
>>>
>>> However, coot fails to read in any of the chains labeled 0-7.
>>>
>>
>> I don't know why this is failing - I will try to make a synthetic PDB file
>> with 60 chains to see if I can reproduce this.
>>
>> Relatively recently Eugene has extended mmdb to  work with the hybrid_36
>> format.  So for now you could go that route.
>>
>> Paul.
>>
>
>

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