> What's the 'proper' way to name nucleotides in Coot? (RNA)

Well, it's actually mmdb which is handling the nucleotide names in this
case. From what I can see the following residue names are recognised as
nucleotides (*):

   "A",  "C",  "G",  "I",   "T",   "U",
  "+A", "+C", "+G", "+I",  "+T",  "+U",
  "DA", "DC", "DG", "DI",  "DT",  "DU",
  "RA", "RC", "RG", "RU", "5NC", "TYD"

Hope this helps,

B

(*) may depend on version, this is for version 1.19 and 1.21

> On Sep 24, 2009, at 9:43 AM, Bernhard Lohkamp wrote:
> 
> >
> > My (educated) guess is that Coot doesnt recognise your 
> nucleotides as
> > such and hence doesnt find any atoms to do the lsq superposition 
> with.> The different nucleotide name 'conventions' strike again....
> >
> > B
> >
> > ***************************************************
> >
> > Dr. Bernhard Lohkamp
> > Assistant Professor
> > Div. Molecular Structural Biology
> > Dept. of Medical Biochemistry and Biophysics (MBB)
> > Karolinska Institutet
> > S-17177 Stockholm
> > Sweden
> >
> > phone: (+46) 08-52487673
> > fax:   (+46) 08-327626
> > email: [email protected]
> >
> > ----- Original Message -----
> > From: Francis E Reyes <[email protected]>
> > Date: Thursday, September 24, 2009 4:54 pm
> > Subject: [COOT] NCS ghosts and map broken?
> > To: [email protected]
> >
> >> Hi all
> >>
> >> It seems that adding ncs ghosts and then ncs maps is broken for my
> >> model / coot combo.
> >>
> >> Coot is at ver 0.6-pre-1 rev 2334.
> >>
> >> Thanks!
> >>
> >>
> >>
> >>
> >>
> >>
> >> This is what phenix.simple_ncs_from_pdb gives me
> >> ==================== Process input NCS or/and find new NCS
> >> ====================
> >>
> >> NCS groups found in parameter file: 1
> >> NCS group 0:
> >>  reference= chain A and (resseq 1:39 or resseq 43:54 )
> >>  selection= chain B and (resseq 1:39 or resseq 43:54 )
> >>
> >> Automatic NCS search:
> >>
> >>
> >> #                       simple_ncs_from_pdb
> >> #
> >> # Find ncs among chains in a PDB file
> >>
> >> # type phenix.doc for help
> >>
> >> Getting NCS from suggested chains:
> >> RMSD for suggested group  ['A', 'B'] [[[1, 39], [43, 54]], [[1,
> >> 39],
> >> [43, 54]]]  is  0.0121907468281
> >>
> >> Updated/new NCS groups:
> >> refinement.ncs.restraint_group {
> >>  reference = chain 'A' and (resseq 1:39 or resseq 43:54 )
> >>  selection = chain 'B' and (resseq 1:39 or resseq 43:54 )
> >> }
> >>
> >>
> >>                  ----------Building NCS restraints----------
> >>
> >> NCS restraint group 1:
> >>  NCS operator 1:
> >>    Reference selection: "chain A and (resseq 1:39 or resseq 
> 43:54 )"
> >>        Other selection: "chain B and (resseq 1:39 or resseq 
> 43:54 )"
> >>    Number of atom pairs: 1103
> >>    Rotation={{-0.500763, -0.865584, 0.000393409},
> >>              {-0.865584, 0.500763, 0.000526561},
> >>              {-0.000652788, -7.68463*^-05, -1}}
> >>    Translation={{-53.5412}, {-30.8968}, {104.68}}
> >>    Histogram of differences:
> >>      0.000454 - 0.008521: 479
> >>      0.008521 - 0.016588: 422
> >>      0.016588 - 0.024655: 146
> >>      0.024655 - 0.032722: 40
> >>      0.032722 - 0.040790: 13
> >>      0.040790 - 0.048857: 3
> >>    RMS difference with respect to the reference: 0.013137
> >>
> >>
> >>
> >>
> >> However when I try to overlay ncs ghosts and a ncs map I get this
> >> from
> >> coot
> >> NCS_controller display chain toggled for imol 0 chain 1 state 1
> >> %%%% ncs_control_display_chain
> >>        There are 1 ghosts
> >>         ighost: 0
> >>        name: "NCS found from matching Chain B onto Chain A"
> >>         chainid: B
> >>         target chain id: A
> >>         display_it_flag 1
> >> %%%%%%%%% calling fill_ghost_info() from c-interface.cc
> >> make_ncs_ghosts_maybe()
> >> INFO:: NCS chain comparison 51/51
> >> First atom of 1103 in first  selection 1/A/1/Gr/ P   altLoc ::
> >> segid :A: pos: (-26.744,-11.257,24.195) B-factor: 106.43
> >> First atom of 1103 in second selection 1/B/1/Gr/ P   altLoc ::
> >> segid :A: pos: (-30.371,-13.357,80.514) B-factor: 107.38
> >> WARNING - no residue for reference residue number 40 A
> >> WARNING - no residue for moving molecule residue number 40 B
> >> WARNING - no residue for reference residue number 41 A
> >> WARNING - no residue for moving molecule residue number 41 B
> >> WARNING - no residue for reference residue number 42 A
> >> WARNING - no residue for moving molecule residue number 42 B
> >> WARNING:: no points to do matching
> >>   find_ncs_matrix returns (LSQ) junk
> >> |         0,         0,         0|
> >> |         0,         0,         0|
> >> |         0,         0,         0|
> >> (         0,         0,         0)
> >>  INFO:: fill_ghost_info Constructed 1 ghosts
> >>      Ghost 0 name: "NCS found from matching Chain B onto Chain A"
> >> INFO:: installing ghost map with name :NCS found from matching
> >> Chain B
> >> onto Chain A
> >> Done install_ghost_map
> >> Reference matcher: 0 and 0
> >> |6.953e-310,6.953e-310,6.953e-310|
> >> |2.238e-314, 1.16e-315,1.334e-322|
> >> |4.244e-314,4.032e-321,         0|
> >> (2.144e-314,         0,         0)
> >> inverse of reference matcher transformation:
> >> |       nan,       nan,       nan|
> >> |       nan,       nan,       nan|
> >> |       nan,       nan,       nan|
> >> (       nan,       nan,       nan)
> >> boxing over uvw = (   -0.6365,   -0.3535,   0.08703) to uvw =
> >> (    0.2349,    0.1764,    0.6158)
> >> INFO:: There were 2 maps contributing to the average
> >> INFO:: rescaling by 0.5
> >> INFO:: 316520 out of 331872 (95.3741%) map points  were masked out
> >> of
> >> NCS average target volume,  chain A
> >> INFO:: made 1 averaged map(s)
> >> Map statistics: mean: nan st.d: nan
> >> Map statistics: min: 0, max: 0
> >> /sw/bin/coot: line 5: 66873 Segmentation fault      
> /sw64/bin/coot-
> >> real "$@"
> >>
> >>
> >>
> >>
> >>
> >>
> >> ---------------------------------------------
> >> Francis Reyes M.Sc.
> >> 215 UCB
> >> University of Colorado at Boulder
> >>
> >> gpg --keyserver pgp.mit.edu --recv-keys 67BA8D5D
> >>
> >> 8AE2 F2F4 90F7 9640 28BC  686F 78FD 6669 67BA 8D5D
> >>
> 
> ---------------------------------------------
> Francis Reyes M.Sc.
> 215 UCB
> University of Colorado at Boulder
> 
> gpg --keyserver pgp.mit.edu --recv-keys 67BA8D5D
> 
> 8AE2 F2F4 90F7 9640 28BC  686F 78FD 6669 67BA 8D5D
> 




***************************************************

Dr. Bernhard Lohkamp
Assistant Professor
Div. Molecular Structural Biology
Dept. of Medical Biochemistry and Biophysics (MBB)
Karolinska Institutet
S-17177 Stockholm
Sweden

phone: (+46) 08-52487673
fax:   (+46) 08-327626
email: [email protected]

Reply via email to