If refmac requires comment after chem_comp it is a bug. It needs to be fixed. I 
will try to fix it for next version - 5.7 series.

Garib



On 30 Nov 2011, at 16:08, Ian Tickle wrote:

> Note that the _chem_comp and _chem_comp_tor blocks are formatted the
> same way if there's only one compound/torsion resp. e.g.:
> 
> _chem_comp.id                  XXX
> _chem_comp.three_letter_code   XXX
> _chem_comp.name                XXX
> _chem_comp.group               .
> _chem_comp.number_atoms_all    7
> _chem_comp.number_atoms_nh     4
> _chem_comp.desc_level          .
> #
> 
> _chem_comp_tor.id                other-001
> _chem_comp_tor.atom_id_1         CL
> _chem_comp_tor.atom_id_2         C
> _chem_comp_tor.atom_id_3         N
> _chem_comp_tor.atom_id_4         H1
> _chem_comp_tor.value_angle       0.0
> _chem_comp_tor.value_angle_esd   1000000.0
> _chem_comp_tor.period            10
> 
> Just as a matter of interest, I take it that Refmac, Libcheck,
> Sketcher etc all accept this fprmat?  I agree that if it's using a
> proper CIF reader it should be able to handle this without blinking.
> I'm pretty sure Refmac doesn't (or didn't when I tested it some time
> ago, maybe it's been fixed), because it requires that the _chem_comp
> block (only) be terminated by a comment line (as in the example):
> that's definitely not in the spec.
> 
> Cheers
> 
> -- Ian
> 
> On 30 November 2011 15:34, Judit Debreczeni <[email protected]> 
> wrote:
>> On 30 November 2011 15:06, Paul Emsley <[email protected]> wrote:
>>> On 30/11/11 10:52, Judit Debreczeni wrote:
>>>> 
>>>> Grade (from Global Phasing) produces cif files with non-loop_
>>>> descriptions of chiral restraints, e.g.:
>>>> 
>>>> _chem_comp_chir.comp_id          INH
>>>> _chem_comp_chir.id               chir_01
>>>> _chem_comp_chir.atom_id_centre   C1
>>>> _chem_comp_chir.atom_id_1        C
>>>> _chem_comp_chir.atom_id_2        C2
>>>> _chem_comp_chir.atom_id_3        O
>>>> _chem_comp_chir.volume_sign      negativ
>>>> 
>>>> 
>>>> This format seems correct to me and actually makes a lot of sense if
>>>> there is only one chiral centre in the molecule.
>>>> 
>>>> Coot, however, ignores such records entirely, so the chirality remains
>>>> unrestrained, cannot be edited in the restraints editor or flipped by
>>>> a keystroke. Using 0.7-pre-1 (revision 3792)  [with guile 1.8.7
>>>> embedded] [with python 2.7.0 embedded].
>>>> 
>>>> Bug? Oversight? Feature?
>>>> 
>>>> 
>>> 
>>> Oversight.  I didn't think that anyone would be so contrary as to format
>>> their chirality in such a way (it seems to me that they must have gone out
>>> of their way to do so - I wonder why...)
>>> 
>> 
>> 
>> Contrary? -- We are talking about the genuine and vanilla RCSB cif
>> parser which I thought should be the gold standard?
>> 
>> 
>>> Anyway, it's something that I should fix.  I'll add it for 0.7.
>>> 
>> 
>> 
>> Thanks.
>> 
>> JED.
>> 

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