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    <TITLE>Harvard Letters - Correspondence with Dr. Edwin Hays</TITLE>
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<BR>
Dr. Edwin Hays<BR>
Director of Research<BR>
Riker Laboratories<BR>
19901 Nordhoff Street<BR>
Northridge, California<BR>
<BR>
Dear Dr. Hays:<BR>
<BR>
Dr, Robert Snowden has informed me that you are the person who could bring
me up to date on mushroom research executed at Riker.<BR>
<BR>
I have been involved in research on psilocybin and the fresh mushroom
psilocybe
Mexicana for several monthes.  Our first step was to collect data from
creative
subjects who could report back to us on their reactions.  We now have data
on over 250 observations and are pretty well acquainted with the factors
which determine positive, insightful or negative reactions.<BR>
<BR>
We are now beginning a new series of investigations on the therapeutic and
educational uses of these substances.  We also plan to continue studies
comparing psilocybin with other consciousness-altering drugs-mescalin,
psilocin,
mushroom extracts and some natural products.<BR>
<BR>
We are interested in your work with mushrooms of greater activity than the
Sandos products.  There is no doubt in my mind that the fresh mushroom
contains
active substances not present in psilocybin.  When you get to the stage
where you have sufficient materials on hand for clinical studies we would
interested in adding your products to our comparative studies.<BR>
<BR>
Any information you could send me describing your work would be appreciated.
 I enclose a copy of a preliminary memorandum describing our earlier work.<BR>
<BR>
                                        Sincerely yours,<BR>
                                        <BR>
                                        Timothy Leary <BR>
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