-Caveat Lector-

http://www.timesonline.co.uk/article/0,,3-601135,00.html
World News

March 06, 2003

Superbug's new strain thrives outside hospitals
By Mark Henderson, Science Correspondent


A NEW strain of the drug- resistant superbug MRSA
has escaped from hospitals to infect thousands of healthy adults across
the United States, hitting hardest among homosexual men.

The bacterium, which normally affects only sick and elderly hospital in-
patients, is striking fit Americans with no links to the hospitals in which it
thrives, raising fears of an epidemic that could spread to Britain. The
germs, which can withstand many common antibiotics, are transmitted by
skin contact, with no need for an open wound.

Outbreaks have been reported in Los Angeles, San Francisco, New York,
Boston and Miami. Most of those affected are homosexual men and prison
inmates, but athletes and schoolchildren involved in contact sports have
also fallen ill. Precise figures for the number of infections are not available,
because MRSA is not a notifiable disease in the United States, but public
health officials believe cases already run into the thousands, with several
deaths.

The disease normally manifests itself as a skin condition, beginning with
sores that resemble insect bites, and progressing to cause painful
abscesses and boils. In rarer cases, when it reaches the lungs or the
bloodstream, it can cause life-threatening pneumonia or septicaemia.

MRSA, which stands for methicillin-resistant Staphylococcus aureus, has
for years been a problem in hospitals, where it infects open wounds and
bedsores, taking advantage of the weakened immune systems of seriously ill
or elderly patients.It is named as a contributory cause of death in 20 per
cent of death certificates issued in British hospitals where staphylococcal
infection was a factor.

The bacteria, however, have never been considered dangerous beyond
the wards. The emergence of a strain that is spreading through the wider
community, details of which are reported today in New Scientist magazine,
has alarmed public health officials on both sides of the Atlantic. Scott
Fridkin, a medical epidemiologist at the US Centres for Disease Control and
Prevention (CDC) in Atlanta, said: “We are greatly concerned that MRSA
has emerged in the community in people with no ties to healthcare.”

Tyrone Pitt, deputy director of the Laboratory of Healthcare Associated
Infections, said that while there was no evidence that the strain had
arrived in Britain, it was a genuine threat. “It is very difficult to predict its
impact. If it manifests itself just as a skin infection, that is not that
threatening. If the result is pneumonia in relatively healthy people, that’s a
completely different scenario,” he said.

The Atlanta centre has yet to complete testing to confirm the strain that
is spreading in the community, but health officials in Los Angeles said all
the outbreaks there appeared to have been caused by a strain first
isolated in New York in 1997. Most of the US cases so far have occurred in
San Francisco and Los Angeles, among homosexual men who have had
multiple sexual partners. The disease is not thought to be sexually
transmitted, but as it is contagious through skin contact, sexual
promiscuity has an indirect effect on risk. Its effects are not confined to
HIV-positive men.

Several prisons in California have reported MRSA outbreaks among inmates,
and there have also been outbreaks in schools, particularly among athletes
involved in contact sports. In Pasadena 50 pupils at one school were
diagnosed with the condition, mostly members of the school’s football
team.

On the rise

MRSA: Methicillin- resistant Staphylococcus aureus

First identified: mid-eighties

Recorded UK cases 1992: 104 2001: 4,904

Confirmed UK deaths 1993: 13 1998: 114

Resistant to: methicillin, oxacillin, nafcillin, cephalosporins

Susceptible to: vancomycin










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Forwarded for your information.  The text and intent of the article
have to stand on their own merits.
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