-Caveat Lector-

Sunday, May 30, 2004

Rutland Herald

Vermont authors contend that virus tainted polio vaccine - May. 29, 2004

By WILSON RING The Associated Press

MONTPELIER - A monkey virus that was introduced to humans in the polio vaccine
that was given to hundreds of millions of people in the 1950s and 1960s is the
cause of a variety of rare cancers appearing now, a new book argues.

"The Virus and the Vaccine" by a Burlington couple argues that the medical
establishment in the United States refused to publicize the danger posed by the
virus after it was first discovered in 1961.

The system used to make polio vaccine was not changed until 1963 and the risk of
contamination was not eliminated completely until 2000. As a result, millions
more Americans were unnecessarily exposed to the virus, known to scientists as
SV40, the book argues.

"Wiping out polio was an incredible public health advance. Nobody would ever
want to see the return of polio," said co-author Jim Schumacher. "The story of
SV40 is that when this virus was discovered in 1961 the response was not 'let's
fix the vaccine,' the response was 'let's not tell anybody about it."'

Schumacher wrote "The Virus and the Vaccine" with his wife Debbie Bookchin, a
longtime Vermont journalist. It was published this month by St. Martin's Press
of New York.

Bookchin and Schumacher say they are not opposed to the use of vaccines.

"Vaccines are a critical public health tool," Bookchin said. "There is no excuse
for not preventing disease through vaccines."

But Schumacher continued, "There is no excuse for not making them safe."

Scientists across the world have come to recognize the dangers of SV40 and many
studies are looking into the virus' link to certain cancers, scientists said.

"The Virus and the Vaccine" argues that SV40 is linked to cancers of the bone
and brain as well as mesothelioma, a virulent and deadly cancer of the lining of
the lungs, and non-Hodgkins lymphoma.

Much of the science in the book is based on research done by Dr. Michele
Carbone, a physician and scientist at Loyola University in Chicago. Carbone has
spent the last decade studying SV40.

He said scientists were initially cautious about accepting the link between SV40
and cancer.

"I think in general the amount of skepticism was very high, but not unusual.
Scientists are skeptical. We went through three scientific reviews," Carbone
said.

"When people started seeing that other people are seeing what we found, this was
something popping up all over the world and others were reproducing our
discoveries, then the skepticism has gone down consistently," he said.

Schumacher said he first became aware of SV40's link to cancer and the polio
vaccine almost a decade ago while working as a law clerk on a divorce case. A
spouse was fighting her husband about being able to make health care decisions
for their children; the wife didn't want her children vaccinated.

And in researching her position Schumacher came across an article about SV40,
the polio vaccine and cancer.

"I went home to Debbie and said 'this is great. We ought to research this.' That
eventually got us to the story of SV40."

Brooke Mossman, a pathologist at the University of Vermont, is studying SV40 and
its connection to mesothelioma, which she says is one of the most deadly
cancers. She is familiar with the thesis of the book by Bookchin and Schumacher.

Mossman said the book would stimulate much-needed further debate in the
scientific community about the dangers of SV40.

"There have been sporadic reports of SV40 in various tumor types. When you put
it all together in terms of the history, the patters of exposure and that it's
in several tumors that are derived from the same types of cells then it makes a
compelling case as SV40 as a human carcinogen," Mossman said. "No one has really
put it together. And that's what they do."

SV40 was discovered in the polio vaccine in 1961 and a scientist at the time
linked the virus to cancer. But it wasn't until 1963 that a different process
was used to make the vaccine, reducing the threat.

Schumacher and Bookchin argue that in the early 1960s the scientific world
didn't want to create fear about one of the greatest medical advancements in
history.

Those early studies were pushed aside and the issue was largely forgotten until
Carbone started studying the issue about a decade ago.

The threat from SV40 contaminated polio vaccine didn't disappear completely
until Jan. 1, 2000 when vaccine producers stopped using monkeys to make the
vaccine.

"Some of the people who have top positions (in the public health community) are
people who 40 years ago made the determination that it was harmless to humans,"
Schumacher said. "The federal government constantly passes judgment on its own
work and has very little incentive to say 'oops we made a mistake."'

Neither the Centers for Disease Control and Prevention nor the National
Institutes of Health responded to questions about the premise of the book.

However, a 2002 study by the Institute of Medicine concluded there was too
little evidence to conclude that SV40 could cause cancer in humans.

And it said that although studies of people who received the vaccine have not
shown increased cancer rates, a connection could not be completely ruled out.

And a National Cancer Institute study reported in 1998 that the millions of
Americans who were given contaminated polio vaccine during the 1950s do not have
a higher incidence of that or other rare cancers some had thought could be
linked to the virus.

Schumacher said he would like to see his book spark debate about SV40 and
increase research funding.

"The original contamination was nobody's fault," Schumacher said. "After 1962,
when there was an alternative, the resistance that we document in our book is
really unconscionable. It is absolutely unconscionable that Americans had no
choice but to receive a polio vaccine made up of mashed up monkey kidneys."

Carbone said he had had no first hand knowledge of the reaction of the
scientific community to SV40 40 years ago. Much of the debate he said he learned
from reading "The Virus and the Vaccine."

"I found those chapters extremely fascinating because 40 years ago was when I
was born," Carbone said.

But he said much of his research and that of others studying SV40 is funded by
the organizations that Schumacher and Bookchin criticize for not doing enough to
correct the problem.

"Things change with time," Carbone said. "I would hope today that such things
would not happen."

   Copyright © 2004 Rutland Herald and Barre-Montpelier Times Argus

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