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A plant dubbed the suicide tree kills many more people in Indian
communities than was previously thought. The warning comes from forensic
toxicologists in India and France who have conducted a review of deaths
caused by plant-derived poisons.
Cerbera odollam, which grows across India and south-east Asia,
is used by more people to commit suicide than any other plant, the
toxicologists say. But they also warn that doctors, pathologists and
coroners are failing to detect how often it is used to murder people.
A team led by Yvan Gaillard of the Laboratory of Analytical Toxicology
in La Voulte-sur-Rh�ne, France, documented more than 500 cases of fatal
Cerbera poisoning between 1989 and 1999 in the south-west Indian
state of Kerala alone. Half of Kerala�s plant poisoning deaths, and one in
10 of all fatal poisonings, are put down to Cerbera.
But the true number of deaths due to Cerbera poisoning in Kerala
could be twice that, the team estimates, as poisonings are difficult to
identify by conventional means.
Unnoticed homicides
Using high-performance liquid chromatography coupled with mass
spectrometry to examine autopsy tissues for traces of the plant, the team
uncovered a number of homicides that would otherwise have gone unnoticed.
This also suggests that some cases put down to suicide may actually have
been murders, they say.
Although the kernels of the tree have a bitter taste, this can be
disguised if they are crushed and mixed with spicy food. They contain a
potent heart toxin called cerberin, similar in structure to digoxin, found
in the foxglove.
Digoxin kills by blocking calcium ion channels in heart muscles, which
disrupts the heartbeat. But while foxglove poisoning is well known to
western toxicologists, Gaillard says pathologists would not be able to
identify Cerbera poisoning unless there is evidence the victim had
eaten the plant. �It is the perfect murder,� he says.
Three-quarters of Cerbera victims are women. The team says that
this may mean the plant is being used to kill young wives who do not meet
the exacting standards of some Indian families. It is also likely that
many cases of homicide using the plant go unnoticed in countries where it
does not grow naturally.
Journal reference: Journal of Ethnopharmacology (vol 95, p
123) | 
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