-Caveat Lector-

http://www.suntimes.co.za:80/1999/05/02/news/news07.htm
-
02 May 1999

Children attacked by flesh-eating bacteria after taking medicine
ANDRE JURGENS

CHILDREN with chickenpox who are fed over-the-counter painkillers run
the risk of being infected by a deadly flesh-eating bacterium.

Doctors say the only way to treat the aggressive bacterium - which
dissolves human flesh - is by amputating infected limbs and treating
patients with antibiotics.

The dangerous link between household medication, chickenpox and the
bacterium was exposed in a medical alert to doctors this week.

"Virtually every child in the country will be exposed to chickenpox at
some or other time," said Dr Stephen Toovey of Medinfo, an organisation
run by South African doctors which monitors international medical trends
and research.

"This flesh-eating bug causes rapid tissue destruction, and entire limbs
can be lost within a matter of hours," he said.

"Amputation and a high dose of antibiotics offer the only hope of
survival."

His warning was triggered by the results of a recent study of children
who were hospitalised within three weeks of an attack of chickenpox in
the US.

Dr Danielle Zerr, of the Children's Hospital in Seattle, headed a team
of scientists who compared 19 children stricken with the bacterium with
29 control children. Those infected were 10 times more likely to have
been given ibuprofen as a painkiller.

Ibuprofen is sold under a number of brand names in South Africa,
including Brufen and Nurofen.

However, the study found that children given paracetamol were  not
infected.

"In the light of these findings it would be prudent to avoid Ibuprofen
and other anti-inflammatories in children suffering from chickenpox,"
said Toovey.

"Paracetamol is equally effective at relieving pain and fever and
appears to be safer in this condition," he said. Paracetamol is
available locally as Panado, Calpol and Fevambol.

The bacterium - officially known as necrotising fasciitis - enters the
body through tiny openings or cuts in the skin and can be lethal if not
quickly diagnosed. It is an infection which comes from the same family
of bacteria that causes common strep throat.

Aching pain, nausea and swollen rashes usually appear within 24 hours of
infection.

Critical symptoms, including a severe drop in blood pressure as the body
goes into shock, develop within four days.

According to the Biological Committee for the Medicines Control Council,
there is no chickenpox vaccine in South Africa, although one has been
submitted for registration.

--

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