In a message dated 4/14/00 3:42:39 AM Central Daylight Time, AOL News writes: << Subj: Scientists Finish Chromosome Maps Date: 4/14/00 3:42:39 AM Central Daylight Time From: AOL News BCC: Ahab42 Scientists Finish Chromosome Maps .c The Associated Press By JESSIE SEYFER SAN FRANCISCO (AP) - In their race to blueprint the human genome, government-sponsored scientists said they have finished ``rough draft'' maps of three complete chromosomes. The announcement Thursday by the Walnut Creek-based Joint Genome Institute made it the first of five publicly funded labs - collectively known as the Human Genome Project - to finish its part of the mapping mission. ``Up until now, we've been struggling in the dark, and now we are in the domain of light,'' said Elbert Branscomb, the institute's chief scientist. The California lab said it has mapped chromosomes 5, 16 and 19, which make up roughly 11 percent of the human genome and contain vital information about kidney disease, various cancers, hypertension and diabetes. ``Three chapters in the reference book of human life are nearly complete,'' said Department of Energy Secretary Bill Richardson. ``This is big stuff and I'm really proud of these guys.'' The 23 pairs of chromosomes in the human genome are made up of coiled strands of DNA. When stretched out, the elegant DNA molecules look like ladders whose rungs are chemical bonds, known as base pairs. Different arrangements of base pairs make up the code for 100,000 known human genes. The genes, in turn, form a blueprint for the assembly of proteins that guide the form and function of cells. Researchers believe that by identifying each gene and determining its effect, medical science will find new ways to treat or prevent birth defects and illnesses. Jasper Rine, a professor of genetics at the University of California, Berkeley, said the importance of Thursday's announcement could not be overstated. ``The human genome sequence, even a rough draft, is a very important beginning to understanding the most important historical document of humanity,'' he said. ``Genome sequences are really a marvelous gift to all basic sciences.'' The news came a week after the private company Celera Genomics, of Rockville, Md., announced it had already accomplished the same goal, also in a rough form. The two sides are in a fierce battle to complete the project first. In contrast to Celera, the federal project is releasing to the public the genetic sequences as they are identified. While the government maps produced so far are only rough estimates of exact gene sequences, scientists said they are still immensely useful tools. On the Net: Joint Genome Institute: http://www.jgi.doe.gov U.S. Department of Energy Human Genome Program: http://www.er.doe.gov/production/ober/genome.html Celera: http://www.celera.com/celerascience/index.cfm AP-NY-04-14-00 0442EDT Copyright 2000 The Associated Press. The information contained in the AP news report may not be published, broadcast, rewritten or otherwise distributed without prior written authority of The Associated Press. Announcement: America Online has added Reuters newswires to News Profiles. To add Reuters articles to your daily news delivery, go to KW: <A HREF="aol://5862:146">News Profiles</A> and click on "Modify Your News Profiles." Then click "Edit" and add Reuters from the list on the left. To edit your profile, go to keyword <A HREF="aol://1722:NewsProfiles">NewsPro files</A>. For all of today's news, go to keyword <A HREF="aol://1722:News">News</A>. >>
Scientists Finish Chromosome Maps .c The Associated Press By JESSIE SEYFER SAN FRANCISCO (AP) - In their race to blueprint the human genome, government-sponsored scientists said they have finished ``rough draft'' maps of three complete chromosomes. The announcement Thursday by the Walnut Creek-based Joint Genome Institute made it the first of five publicly funded labs - collectively known as the Human Genome Project - to finish its part of the mapping mission. ``Up until now, we've been struggling in the dark, and now we are in the domain of light,'' said Elbert Branscomb, the institute's chief scientist. The California lab said it has mapped chromosomes 5, 16 and 19, which make up roughly 11 percent of the human genome and contain vital information about kidney disease, various cancers, hypertension and diabetes. ``Three chapters in the reference book of human life are nearly complete,'' said Department of Energy Secretary Bill Richardson. ``This is big stuff and I'm really proud of these guys.'' The 23 pairs of chromosomes in the human genome are made up of coiled strands of DNA. When stretched out, the elegant DNA molecules look like ladders whose rungs are chemical bonds, known as base pairs. Different arrangements of base pairs make up the code for 100,000 known human genes. The genes, in turn, form a blueprint for the assembly of proteins that guide the form and function of cells. Researchers believe that by identifying each gene and determining its effect, medical science will find new ways to treat or prevent birth defects and illnesses. Jasper Rine, a professor of genetics at the University of California, Berkeley, said the importance of Thursday's announcement could not be overstated. ``The human genome sequence, even a rough draft, is a very important beginning to understanding the most important historical document of humanity,'' he said. ``Genome sequences are really a marvelous gift to all basic sciences.'' The news came a week after the private company Celera Genomics, of Rockville, Md., announced it had already accomplished the same goal, also in a rough form. The two sides are in a fierce battle to complete the project first. In contrast to Celera, the federal project is releasing to the public the genetic sequences as they are identified. While the government maps produced so far are only rough estimates of exact gene sequences, scientists said they are still immensely useful tools. On the Net: Joint Genome Institute: http://www.jgi.doe.gov U.S. Department of Energy Human Genome Program: http://www.er.doe.gov/production/ober/genome.html Celera: http://www.celera.com/celerascience/index.cfm AP-NY-04-14-00 0442EDT Copyright 2000 The Associated Press. The information contained in the AP news report may not be published, broadcast, rewritten or otherwise distributed without prior written authority of The Associated Press. Announcement: America Online has added Reuters newswires to News Profiles. To add Reuters articles to your daily news delivery, go to KW: <A HREF="aol://5862:146">News Profiles</A> and click on "Modify Your News Profiles." Then click "Edit" and add Reuters from the list on the left. To edit your profile, go to keyword <A HREF="aol://1722:NewsProfiles">NewsProfiles</A>. For all of today's news, go to keyword <A HREF="aol://1722:News">News</A>.
