WASHINGTON (Reuters) - Brain scans of U.S. veterans who returned from the
Gulf War complaining of illness show evidence of significant brain-cell loss,
researchers reported on Thursday.

Sick veterans had 20 percent fewer cells in the brain stem, 12 percent fewer
in the right basal ganglia and 5 percent fewer in the left basal ganglia, a
team at the University of Texas Southwestern Medical Center at Dallas
reported.

They said the amount of loss was comparable to that seen in patients with
brain diseases like amyotrophic lateral sclerosis (ALS or Lou Gehrig's
disease), multiple sclerosis, dementia and other degenerative neurological
disorders, although the brain areas affected are different.

Dr. Robert Haley and colleagues did magnetic resonance spectroscopy (MR)
scans on 22 members of a Naval Reserve construction battalion, commonly known
as Seabees, and compared their findings to scans on 18 healthy veterans from
the same

battalion.

They repeated the experiment on six Gulf War Army veterans living in Dallas
who doctors said had Gulf War Syndrome.

MR. spectroscopy uses radio waves to measure chemical activity in the brain.

``Finding the same level of brain cell abnormality in the veterans from a
different branch of service and a different

part of the country increases the likelihood that the findings are widespread
among the nation's veterans,'' Haley said in a statement.

Writing in the journal Radiology, the researchers said they could link the
brain damage to symptoms found in ill veterans such as joint pain, fatigue,
dizziness and mental confusion.

``A common question is whether these levels of brain-cell loss found in these
veterans are clinically important,'' Hale said.

``You need to ask yourself if you would be willing to give up 5 percent to 25
percent of the brain cells in vital parts of your brain that serve as the
relay station for all automatic and subconscious functions of your brain,''
he added.

``When you sustain such brain-cell losses, you get a host of subtle
malfunctions of all systems of the body.''

Previous magnetic resonance imaging (MRI) on the veterans found no visible
structural changes to their brains. MR. spectroscopy looks at function as
well as structure.

Haley and his colleagues, who get Defense Department funding, defined three
Gulf War syndromes in the Journal of the American Medical Association in
1997.

They said syndrome 1, commonly found in veterans who wore
pesticide-containing flea collars, is marked by impaired cognition.

Syndrome 2, called confusion-ataxia is the most severe and debilitating
syndrome. They found it among veterans who said they were exposed to
low-level nerve gas and experienced side effects from anti-nerve gas
pyridostigmine (PB), tablets.

Syndrome 3, characterized by central pain, is found in veterans who wore
insect repellent with high concentrations of DEET and who experienced side
effects from the PB tablets.

For Thursday's study Haley's team used veterans with the so-called syndrome
2.

01:38 05-25-00

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