-Caveat Lector-
Cloning teams cross pig and human DNA
http://www.sunday-times.co.uk/news/pages/sti/2000/10/08/stifgnaus01001.html
SCIENTISTS have successfully produced an embryonic pig-human
hybrid. Human DNA was inserted into pig cells which became tiny
embryos, write Jonathan Leake and Nick Fielding.
The researchers have not revealed what happened to them, but
suggest they could have been grown further by being implanted
into a womb - and that either a pig or a human mother would have
been suitable.
The intentions of the researchers are not made clear in an
application they have submitted to the European Patent Office.
However, such embryos would be ideal for research into
therapeutic cloning, when cells are cloned, grown into tissues
such as nerve cells and then used to treat a patient.
The researchers, from Stem Cell Sciences in Australia and
Biotransplant in America, both big players in the biotechnology
industry, took a cell from a human foetus, extracted the nucleus
and then inserted it into a pig's egg cell. Two embryos were
grown to the 32-cell stage, which took a week.
Experts in medical ethics are deeply concerned about the patent
application, which has a strong chance of being granted. They say
the research exploits loopholes in European law. It is not
illegal because the embryo is not technically human.
Dr Richard Nicholson, editor of the Bulletin of Medical Ethics,
said: "This kind of research depends on devaluing human beings."
Nobody knows whether the hybrid embryos could have be-come living
beings. They would be much more human than pig because about 97%
of DNA is in the nucleus, which was human. There would, however,
be some effect from the 3% of DNA from the pig.
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